This research aims to evaluate whether a basketball-specific warm-up (Basket-Up) provides immediate benefits in terms of the essential physical performance requirements of basketball and to compare these effects to those obtained from FIFA 11+. In total, 95 highly trained basketball athletes (49 women, 46 men), aged between 13 and 17, were randomly divided to either perform the FIFA 11+ program (n = 48) or the Basket-Up program (n = 47). Immediate evaluation encompassed the assessment of vertical jump (countermovement jump), agility (Lane Agility Test), and 20 m sprint. A two-way mixed analysis of variance was conducted with time (preintervention and postintervention), sex (men and women), and training group (FIFA 11+ and Basket-Up) as the within- and between-participant factors, respectively. Agility (p < 0.001, F = 66.759) and jumping (p < 0.001, F = 78.062) outcomes exhibited significant differences between pre- and postintervention values in both groups. Basket-Up agility values were significantly higher than those from FIFA 11+ (p = 0.001, F = 12.998). The implementation of a specific basketball warm-up program (Basket-Up) appears to be both safe and effective in enhancing immediate athletic performance among highly trained young basketball athletes. Moreover, the effects of this program are comparable to those obtained by a nonspecific basketball warm-up (FIFA 11+) in terms of sprint and jumping performance but demonstrate superiority in agility outcomes, favoring the Basket-Up program.