Background: Suicide is a health problem among patients diagnosed with schizophrenia. Telehealth technology has become an emerging intervention that may offer opportunities to reach this at-risk group. However, to consider the implementation of telehealth systems in the prevention of suicidal behaviors in patients diagnosed with schizophrenia, a review of the evidence is required. The present aim was to explore the effectiveness of telephone-based suicide prevention programs among patients with schizophrenia and related disorders. Methods: A bibliographic search was carried out in the PubMed, PsycInfo, Scopus and Web of Science electronic databases following PRISMA guidelines. Two reviewers performed the selection, data extraction and methodological quality assessment. A total of 352 articles were retrieved, of which five studies met the eligibility criteria. Results: Globally, an adherence was observed ranging from 78 to 100%. Three studies reported a reduction in suicidal ideation and two studies showed a reduction in the risk of relapse observed in the intervention group compared to a control group. Conclusions: In accordance with the limited data available, the use of a telephone contact approach appears to be feasible and effective in schizophrenia patients with suicidal behaviors. The preliminary evidence also suggests that this system appears to reduce suicidal ideation. Further research is required to design evidence-based future interventions and to determine whether this approach can improve patient outcomes.

• 14% of Spanish young adults showed hesitancy/reluctance to vaccination against the SARS-CoV-2. • Main predictors of vaccination intention were attitudes, trust, and information. • Main predictors accounted for 41% of the variability regarding intention to get vaccinated. • Main predictors made it possible to detect vaccination intention with 86% accuracy. • Adequate management of public information is critical to manage the hesitancy to vaccination in young adults.

Background/Objectives: Psychological pain—also termed psychache or mental pain—has been suggested to constitute a relevant factor in the emergence of suicidal behaviour. Despite conceptual advances, empirical research on interventions specifically designed to alleviate psychological pain in individuals who have attempted suicide remains scarce. The present scoping review maps existing psychological and pharmacological interventions targeting psychological pain, identifies their core components, delineates gaps for future research, and proposes a therapeutic intervention protocol. Methods: Literature was searched through PubMed, PsycInfo, and ClinicalTrials.gov (until October 2025) using combinations of the terms suicide, psychache, psychological pain, intervention, treatment, therapy, pharmacological treatment, and psychotherapy. Both randomised controlled trials, non-randomised controlled trials, and literature reviews were included. Results: Evidence indicates that few interventions explicitly target psychological pain. Most suicide-specific therapies indirectly address components of psychological pain—such as unbearable affect, loss of meaning, and social disconnection. Narrative-based, emotion regulation, and acceptance-based therapies appear promising. Emerging pharmacological approaches may relieve psychological pain; however, further evidence is required. Conclusions: Integrating psychological pain as a therapeutic focus—through narrative, tolerance-building, and relational strategies—may enhance post-attempt interventions. Future trials should systematically measure psychological pain and test its role as a mediator of suicidal outcomes.

Introduction: During Covid-19, high prevalence of distress was reported among students, suggesting that they may be at higher risk than the general population of developing psychological disorders in confinement situations. Methods: We conducted a systematic search of four databases (PsycINFO, PubMed, SCOPUS, and Web of Science) for articles published from January 2020 to May 2022. Risk of bias was assessed using the Joanna Briggs Institute (JBI) checklist. Random effects meta-analyses of the reported proportions of college students with clinically significant symptoms of anxiety, depression and stress were carried out, and between-studies heterogeneity was also analysed. Results: 73 studies (N=209.761) were included for meta-analysis. The estimated proportion of college students with clinically significant short-term symptoms was 34% for anxiety (95% CI [29%,39%]; I ² =99.75%), 38% for depression (95% CI [33%,44%; I ² = 99.71%), and 54% for stress (95% CI [46%,62%]; I ² = 99.57%). The estimated proportion of college students with clinically significant long-term symptoms was 37% for anxiety (95% CI [32%,42%]; I ² = 97.92%), 31% for depression (95% CI [23%,41%]; I ² = 99.49%) and 41% for stress (95% CI [25%,59%]; I ² = 99.29%) were found. Several methodological and sociodemographic moderators accounted for heterogeneity in the observed prevalences. Limitations: The heterogeneity of study findings suggest that the results should be interpreted with caution. Conclusion: The current evidence shows that approximately one-third of college students experienced distress, further where we can infer that there was no evidence of a worsening in mental health derived from a cumulative effect during the pandemic. PROSPERO: CRD420222233036.

Objectives: Suicide is a leading cause of preventable death worldwide. Evidence supports the impact of providing active contact for individuals who have attempted suicide. The current systematic review and meta-analyses aim to investigate the effects of suicide prevention strategies implemented through remote and synchronous technology-based interventions. Design: Systematic review, narrative synthesis and meta-analysis. Data sources: Electronic databases (PubMed, PsycINFO, Scopus and Web of Science) and grey literature sources (ClinicalTrials.gov and Google Scholar) were searched until December 2024. Eligibility criteria: Eligible articles assessed suicide prevention interventions for participants over 12 years with prior suicidal behaviour. Eligible study designs included randomised controlled trials and non-randomised clinical trials published in English or Spanish. Data extraction and synthesis: Screening, selection process, data extraction and risk of bias assessment were performed independently by two reviewers. Data on suicide-related factors and adherence to treatment were extracted. Meta-analyses were conducted to determine effect sizes (Hedges’ g) for suicidal ideation, risk ratios (RR) for suicide attempts and Peto odds ratios (OR) for suicide. Heterogeneity was assessed using the Cochrane’s Q test, tau ² statistic and I ² value. Publication bias was investigated employing funnel plots and Egger’s test. Results: A total of 28 studies, comprising 10 015 participants in the intervention group and 10 726 in the comparison group, were included in the systematic review and meta-analyses. Synchronous remote-based interventions were effective in preventing repeated suicide attempts at 1 month (RR 0.73, 95% CI 0.62 to 0.85, I ² =0.0%, Q=0.70, tau ² =0.00), 6 months (RR 0.56, 95% CI 0.34 to 0.95, I ² =85.4%, Q=54.92, tau ² =0.36) and 12 months (RR 0.68, 95% CI 0.49 to 0.96, I ² =87.6%, Q=72.63, tau ² =0.27). Additionally, these interventions were associated with a reduction in suicide-related deaths at 18 months (Peto OR 0.18, 95% CI 0.08 to 0.44, I ² =0.0%, Q=0.03, tau ² =0.00). Effects on suicidal ideation were not statistically significant at any time point (Hedges’ g −0.07 to −0.28, I ² =0.0 to 69.3%, Q=1.16 to 7.38, tau ² =0.00 to 0.14). Conclusions: Synchronous remote-based interventions demonstrate a potential benefit in preventing suicide attempts and deaths by suicide and may serve as an adjunct to usual treatment; however, the effect on suicidal ideation appears limited. The observed heterogeneity warrants caution when interpreting these findings. Future research should prioritise methodological enhancements to improve the quality and consistency of evidence, as well as investigate the mediating processes underlying their effectiveness in reducing suicidal behaviour. PROSPERO registration number: CRD42021275044.

Background Suicide is among the leading causes of preventable death worldwide. The impact of suicide affects personal, social, and economic level. Therefore, its prevention is a priority for public health systems. Previous studies seem to support the efficacy of providing active contact to persons who have made a suicide attempt. The current systematic review and meta-analysis aims to investigate the efficacy of distance suicide prevention strategies implemented through synchronous technology-based interventions. Methods This protocol is designed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). The bibliographic searches will be conducted in the databases MEDLINE/PubMed, PsycInfo, Scopus, and Web of Science until April 2022, with no restrictions on the publication period and limited to publications in English or Spanish. Two reviewers will independently conduct study screening, selection process, data extraction, risk of bias (RoB), and methodological quality assessment. Conclusions Telematics suicide prevention has been an emergent field for years, although there is currently no evidence that synthesises the efficacy of synchronous remote-based interventions. This protocol outlines the methods of a planned research that will extend knowledge derived from the current available evidence. It will provide guidance to clinical practice and encourage further research. Systematic review registration This protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO), under the identification number CRD42021275044.