Laura Patrussi obtained her degree in Biological Sciences, with a cellular and molecular focus, at the University of Siena in 2001. She obtained her PhD in molecular immunology at the University of Siena. Her research has been focused, over the past 17 years, on the dissection of signaling pathways in lymphocytes and the identification of signaling dysfunctions in immune-related diseases. She contributed seminal findings on the multiple roles of the Shc protein family in lymphocyte activation, apoptosis, and chemotaxis. Her recent work, which focused on the characterization of p66Shc in lymphocytes, has led to the implication of p66Shc deficiency in the onset and progression of CLL. Her expertise in this research field is witnessed by the quality and continuity of her track record (40 publications in high-impact peer-reviewed journals). She has actively participated in the dissemination of science, as shown by a long list of oral and poster presentations given at international and national conferences. She is currently the leader of a research group composed of a PhD student, a post-doc fellow, and bachelor's/master's degree students, which is dissecting the role of p66Shc as a modulator of the interplay of CLL B cells with the stromal microenvironment. Her organizational skills are witnessed by the organization of the final meeting of the FIRB 2011 project, which was held in Siena (Nov, 2011).