Marouane AOUJI

Dr. Marouane AOUJI

Biology, Université Ibn-Tofail, Kenitra, Rabat-Salé-Kénitra, Morocco
orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 November 2023 in BioMedicine
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Journal Article
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Marouane AOUJIMarouane AOUJI
Marouane AOUJI
ARAmine Rkhaila
Amine Rkhaila
BBBouchra Bouhaddioui
Bouchra Bouhaddioui
MZMalak Zirari
Malak Zirari
HHHala Harifi
Hala Harifi
RBRachid Bengueddour
Rachid Bengueddour
Mucus is a substance made by snails that serves a variety of purposes and is increasingly employed in the medical and cosmetic industries. It includes bioactive compounds with a range of biological characteristics that could be useful in the treatment of particular issues. This study assessed the wound-healing efficiency, antibacterial activity, chemical and mineral composition of Helix aspersa Müller slime. Inductively Coupled Argon Plasma Atomic Emission Spectrometry (ICP-OES) was used for mineral analysis, while Gas chromatography coupled to mass spectrometry (GC-MS) analysis was used for chemical characterization. The findings showed that the H. aspersa Müller slime had inhibitory activity on the test samples. Additionally, it revealed significant healing activity. These findings point to the chemical composition and various biological activities of the H. aspersa Müller slime, which may be related to the animal’s particular functions and be useful for medical applications. Our findings suggest that the H. aspersa Müller slime has biological effects related to antimicrobial activities and wound healing, and they pave the way for a more thorough investigation of its potential therapeutic effects.

29 August 2023 in Molecules
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Marouane AOUJIMarouane AOUJI
Marouane AOUJI
Hamada ImtaraHamada Imtara
Hamada Imtara
ARAmine RKHAILA
Amine RKHAILA
BBBouchra Bouhaddioui
Bouchra Bouhaddioui
AAAhmad Alahdab
Ahmad Alahdab
RBRachid Bengueddour
Rachid Bengueddour
Humans consume snail flesh as part of their diet. To assess its nutritional value and toxicity, chemical analyses were conducted to confirm the presence of protein, total and reduced carbohydrates, fat, fatty acid composition and mineral components. Furthermore, an acute toxicity study was carried out to determine the safety of Helix aspersa Müller snail flesh. H. aspersa Müller snail flesh exhibits a high nutritional content, a good ω3/ω6 ratio and higher levels of unsaturated fatty acids. Various minerals have been found in the flesh of H. aspersa Müller. Around 76.91 kcal, or 3.84% of the energy of a daily meal of 2000 kcal, are present in 100 g of this flesh. The evaluation of the antioxidant capacity indicated that the flesh’s extracts contained a large quantity of antioxidant biomolecules. Administration of the aqueous extract of H. aspersa Müller flesh didn’t cause death in laboratory rats, indicating that the lethal dose 50 is greater than 2000 mg·kg−1 body weight. The consumption of the flesh of H. aspersa Müller is highly recommended for human consumption due to its high concentration of nutrients and essential elements, as well as unsaturated fats, and due to its safety.

5 February 2024 in International Journal of Secondary Metabolite
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MZMalak Zirari
Malak Zirari
Marouane AOUJIMarouane AOUJI
Marouane AOUJI
MZMeryem ZOUARHI
Meryem ZOUARHI
ADAhmed Dermaj
Ahmed Dermaj
HEHamid Erramli̇
Hamid Erramli̇
NMNouredine EL Mejdoub
Nouredine EL Mejdoub
The aim of this research was to explore the chemical composition and antioxidant activities of etheric extracts of Abies marocana. A Soxhlet apparatus was used to extract bioactive molecules from the various parts of the plant. Furthermore, the levels of antioxidant compounds were quantified, while the Gas chromatography was utilized to determine the chemical constituents of the extracted molecules. The extracts were evaluated for their antioxidant properties using the DPPH radical scavenging method and the total antioxidant capacity test. The levels of polyphenols varied across different parts of the plant, ranging from 2.474 ± 0.029 mg.g-1 DM in needles to 4.207 ± 0.008 mg.g-1 DM in twigs. Flavonoids were most abundant in needles 0.140 ± 0.001 mg.g-1 DM and least abundant in cones 0.069 ± 0.007 mg.g-1 DM. Tannins had the highest concentration in twigs 2.608 ± 0.114 mg.g-1 DM, followed by cones 1.948 ± 0.037 mg.g-1 DM and needles 1.512 ± 0.09 mg.g-1 DM. A chromatographic analysis revealed that 56 components were in the samples, with terpene compounds being the most abundant in the different organs. In terms of antioxidant activity, the extract derived from twigs exhibited the strongest antioxidant capacity 49.377 ± 0.371 mg EAA.g-1 DM, followed by cones 35.129 ± 0.084 mg EAA.g-1 DM and needles 13.663 ± 0.084 mg EAA.g-1 DM. Alternatively, the IC50 values for the three organs were found to be in the range of 3844 to 5047.67 µg.mL-1. The results highlight the potential phytopharmaceutical value of A. marocana due to the presence of diverse phyto-components.

1 February 2024 in Ecological Engineering & Environmental Technology
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AFAbderrahim Fiouz
Abderrahim Fiouz
SCSaïd Chakiri
Saïd Chakiri
ANAyoub Najem
Ayoub Najem
MHMounir El Hezzat
Mounir El Hezzat
MAMohamed Ben Abbou
Mohamed Ben Abbou
Abdelkader ZarroukAbdelkader Zarrouk
Abdelkader Zarrouk
In recent decades, the province of Taza has undergone extensive agricultural modernization, marked by an increase in industrial units such as modern oil mills and olive canneries. At the same time, rapid population growth has exacerbated an important problem, the deterioration of the quality of...

2 August 2024 in ACS Omega
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Journal Article
Open access
Marouane AOUJIMarouane AOUJI
Marouane AOUJI
MZMalak Zirari
Malak Zirari
Hamada ImtaraHamada Imtara
Hamada Imtara
ARAmine Rkhaila
Amine Rkhaila
BBBouchra Bouhaddioui
Bouchra Bouhaddioui
RBRachid Bengueddour
Rachid Bengueddour
Snail flesh is a highly nutritious and easily digestible food commonly integrated into the human diet. In this study, snails belonging to the Helix aspersa Muller species were used to determine their chemical composition and evaluate the antioxidant and antibacterial activities of their flesh using successive maceration extractions with three solvents of different polarities. Biomolecules were analyzed spectrophotometrically, and their chemical compositions were determined by using gas chromatography coupled with mass spectroscopy. The antioxidant activity was assessed using three tests: DPPH, iron-reducing power test, and total antioxidant activity. The ethanol extract was found to be the most effective, with a high yield and high biomolecule content compared with other extracts. The extracts showed a significant amount of antioxidants, ranging from 3.14 to 7.04 mg AAE g(-1) of dry matter, according to the total antioxidant activity assay. The DPPH scavenging capacity showed a reduction of the radical, with inhibitory concentrations ranging from 507.07 to 829.49 mu g mL(-1). In contrast, the iron-reducing power ranged from 67.98 to 424.74 mu g mL(-)1. All of the strains studied responded favorably to the antimicrobial effects of H. aspersa extracts, with a zone of inhibition ranging from 8.48 to 15.53 mm. Additionally, at approximately 15 mg mL(-1), the ethanolic extract had the lowest minimum inhibitory concentration against Pseudomonas aeruginosa. H. aspersa Muller flesh is rich in biomolecules with antioxidant and antibacterial activities, which could justify its use as a natural product and in therapeutic applications in the food industry.

5 February 2024 in International Journal of Secondary Metabolite
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Journal Article
Open access
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SRSara Razzak
Sara Razzak
Marouane AOUJIMarouane AOUJI
Marouane AOUJI
CSChaima Sabri
Chaima Sabri
HBHiba Benchehida
Hiba Benchehida
MTMariame Taibi
Mariame Taibi
YTYouness Taboz
Youness Taboz
The current study focuses on the study of phenolic compounds in methanol, dichloromethane, and chloroform extracts as solvents with increasing polarity, in order to quantify the secondary metabolites of Opuntia ficus indica pads collected from three Moroccan sites (Oulad Boubker, Imzouren, and Skoura). The findings showthat betalains and carotenoids were present, in varying amounts depending on the study area. The methanolic extracts had the concentrations of compounds. When analyzing the chemical composition using Gas Chromatography-Mass Spectrometry, it was found that linoleic acid was the unsaturated fatty acid accounting for 14.279%. Palmitic acid, fatty acid derivatives and alkanes were also detected in all regions. Among the extracts Imzouren had the concentration of fatty acids (24.874%) followed by Oulad Boubker (13.907%) and Skoura (13.319%). However, oleic acid was detected only in the extract of Skoura. Hence, we were able to confirm that the chemical differences among the various Opuntia extracts were primarily influenced by the selection of the extracting solvent and the prevailing climatic and geographical factors.