Mathilde Lepoitevin

Dr. Mathilde Lepoitevin

institut des materiaux poreux de Paris, Ecole Normale Superieure, ESPCI Paris, CNRS, PSL University, 75005 Paris, France
orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2017 in Advances in Colloid and Interface Science
Verified
Journal Article
Closed access
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
TMTianji Ma
Tianji Ma
Mikhael BECHELANYMikhael BECHELANY
Mikhael BECHELANY
JJJean-Marc Janot
Jean-Marc Janot
Sebastien BalmeSebastien Balme
Sebastien Balme

11 June 2021 in Materials Chemistry Frontiers
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Journal Article
Closed access
PDF file
XMXin Ma
Xin Ma
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
CSChristian Serre
Christian Serre
This mini review summarises the progress in the field of MOFs and their use in biomedical applications, from their early discovery and conception, to more recent achievements including promising in vivo applications. It looks to identify in detail the main advantages and current limitations of MOFs, with emphasis on their synthesis, stability (chemical, colloidal) and toxicity issues, as well as proposing guidelines to circumvent these challenges in the near future, in order to meet the demanding criteria of clinical stage trials.

10 October 2024 in Advanced Healthcare Materials
Verified
Journal Article
Open access
ZYZhihao Yu
Zhihao Yu
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
CSChristian Serre
Christian Serre
Over the past two decades, iron‐based metal–organic frameworks (Fe‐MOFs) have attracted significant research interest in biomedicine due to their low toxicity, tunable degradability, substantial drug loading capacity, versatile structures, and multimodal functionalities. Despite their great potential, the transition of Fe‐MOFs–based composites from laboratory research to clinical products remains challenging. This review evaluates the key properties that distinguish Fe‐MOFs from other MOFs and highlights recent advances in synthesis routes, surface engineering, and shaping technologies. In particular, it focuses on their applications in biosensing, antimicrobial, and anticancer therapies. In addition, the review emphasizes the need to develop scalable, environmentally friendly, and cost‐effective production methods for additional Fe‐MOFs to meet the specific requirements of various biomedical applications. Despite the ability of Fe‐MOFs–based composites to combine therapies, significant hurdles still remain, including the need for a deeper understanding of their therapeutic mechanisms and potential risks of resistance and overdose. Systematically addressing these challenges could significantly enhance the prospects of Fe‐MOFs in biomedicine and potentially facilitate their integration into mainstream clinical practice.

1 June 2014 in Applied Clay Science
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Journal Article
Closed access
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
MJMaguy Jaber
Maguy Jaber
Regis GueganRegis Guegan
Regis Guegan
JJJean-Marc Janot
Jean-Marc Janot
PDPhilippe Dejardin
Philippe Dejardin
Sebastien BalmeSebastien Balme
Sebastien Balme

24 August 2016 in Langmuir
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Journal Article
Closed access
Sebastien BalmeSebastien Balme
Sebastien Balme
PCPierre Eugène Coulon
Pierre Eugène Coulon
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
BCBenoît Charlot
Benoît Charlot
NYNaresh Yandrapalli
Naresh Yandrapalli
JJJean-Marc Janot
Jean-Marc Janot

27 February 2015 in Chemical Communications
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Journal Article
Closed access
PDF file
Mathilde LepoitevinMathilde Lepoitevin
Mathilde Lepoitevin
GNGael Nguyen
Gael Nguyen
Mikhael BECHELANYMikhael BECHELANY
Mikhael BECHELANY
EBEmmanuel Balanzat
Emmanuel Balanzat
JJJean-Marc Janot
Jean-Marc Janot
Sebastien BalmeSebastien Balme
Sebastien Balme
Here we propose a new approach to tailor nanopores, which combines both pH gating and sensing properties.