Nnabueze Darlington Nnaji

Dr. Nnabueze Darlington Nnaji

University of Birmingham, Birmingham, UK
orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 April 2023 in SN Applied Sciences
Verified
Journal Article
Open access
PDF file
Nnabueze Darlington NnajiNnabueze Darlington Nnaji
Nnabueze Darlington Nnaji
Helen OnyeakaHelen Onyeaka
Helen Onyeaka
TMTaghi Miri
Taghi Miri
CUChinenye Ugwa
Chinenye Ugwa
This paper reviews plants and microorganisms removal of heavy metals from contaminated sites through bioaccumulation. Increased industrial activities have led to the uncontrolled release of metals into the environment, resulting in a global increase in metal pollution. Heavy metals are also consumed from the surface of glasses over a prolonged period of use. Heavy metal pollution is a serious problem that can have wide-ranging and long-lasting impacts on human health and the environment. Therefore, effective removal and remediation of heavy metal pollution are crucial to protect human and ecological health. Traditional methods of heavy metal removal, such as chemical treatment and physical removal, can be costly and can also have negative impacts on the environment. The utilization of plants and microorganisms for bioremediation of metal-polluted environments has proven effective for removing metals through accumulation and/or detoxification. This method is effective, economical, versatile, and environmentally friendly. Bioaccumulation utilizes plants and microorganisms to absorb and remove heavy metals from contaminated sites. This method is not only cost-effective but also helps to minimize the environmental impact of heavy metal pollution. Additionally, bioaccumulation can be used in combination with other techniques, such as phytostabilization and phytodegradation, to further improve the efficiency of heavy metal removal. The paper also discusses the use of plants and microorganisms in the removal of heavy metals from water and soil through biomagnification and bioconcentration. Techniques such as phytoaccumulation, phytostimulation, phytodegradation, phytovolatilization, phytostabilization, and phytofiltration are also discussed as effective ways of remediation of heavy metal contaminated sites.

18 December 2024 in Sustainability
Verified
Journal Article
Open access
PDF file
Nnabueze Darlington NnajiNnabueze Darlington Nnaji
Nnabueze Darlington Nnaji
CAChukwudi U Anyanwu
Chukwudi U Anyanwu
Taghi MiriTaghi Miri
Taghi Miri
Helen OnyeakaHelen Onyeaka
Helen Onyeaka
Heavy metal pollution from industrial activities and poor waste disposal poses significant environmental and health threats to humans and animals. This calls for sustainable approaches to the cleanup of heavy metals. This review explores metal tolerance mechanisms of bacteria such as the formation of biofilms, efflux systems, and enzymatic detoxification. These mechanisms allow bacteria communities to adapt and survive in contaminated environments. These adaptations are enhanced by mutations in the bacteria genes and by horizontal gene transfers, enabling bacteria species to survive under environmental stress while simultaneously contributing to nutrient cycling and the decomposition of organic matter. This review further explores the symbiotic interactions between bacteria, plants, and animals. These relationships enhance the metal tolerance ability of the different living organisms involved and are also very important in the bioremediation and phytoremediation of heavy metals. Plant growth-promoting rhizobacteria, Rhizobium, and Bacillus species are very important contributors to phytoremediation; they improve heavy metal uptake, improve the growth of roots, and plants resilience to stress. Moreover, this review highlights the importance of genetically engineered bacteria in closed-loop systems for optimized metal recovery. This offers environmentally friendly and sustainable options to the traditional remediation methods. Engineered Cupriavidus metallidurans CH34 and Pseudomonas putida strain 15420352 overexpressing metallothioneins have shown enhanced metal-binding capabilities, which makes them very effective in the treatment of industrial wastewaters and in biosorption applications. The use of engineered bacteria for the cleanup of heavy metals in closed-loop systems promotes the idea of a circular economy by recycling metals, thus reducing environmental waste. Multidisciplinary research that integrates synthetic biology, microbial ecology, and environmental science is very important for the advancement of metal bioremediation technologies. This review’s analysis on bacterial metal tolerance, symbiosis, and bioengineering strategies offers a pathway to effective bioremediation options, for the reclamation of heavy metal-polluted environments while promoting sustainable environmental practices.

14 November 2024 in Antibiotics
Verified
Journal Article
Open access
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OIOnyinye Ifedinezi
Onyinye Ifedinezi
Nnabueze Darlington NnajiNnabueze Darlington Nnaji
Nnabueze Darlington Nnaji
Christian AnumuduChristian Anumudu
Christian Anumudu
Chiemerie Theresa EkwuemeChiemerie Theresa Ekwueme
Chiemerie Theresa Ekwueme
Chijioke Christopher UhegwuChijioke Christopher Uhegwu
Chijioke Christopher Uhegwu
Helen OnyeakaHelen Onyeaka
Helen Onyeaka
Antimicrobial resistance (AMR) is a serious global health issue, aggravated by antibiotic overuse and misuse in human medicine, animal care, and agriculture. This study looks at the different mechanisms that drive AMR, such as environmental contamination, horizontal gene transfer, and selective pressure, as well as the severe implications of AMR for human and animal health. This study demonstrates the need for concerted efforts across the scientific, healthcare, agricultural, and policy sectors to control the emergence of AMR. Some crucial strategies discussed include developing antimicrobial stewardship (AMS) programs, encouraging targeted narrow-spectrum antibiotic use, and emphasizing the significance of strict regulatory frameworks and surveillance systems, like the Global Antimicrobial Resistance and Use Surveillance System (GLASS) and the Access, Watch, and Reserve (AWaRe) classification. This study also emphasizes the need for national and international action plans in combating AMR and promotes the One Health strategy, which unifies environmental, animal, and human health. This study concludes that preventing the spread of AMR and maintaining the effectiveness of antibiotics for future generations requires a comprehensive, multidisciplinary, and internationally coordinated strategy.

7 April 2025 in Journal of Agriculture and Food Research
Verified
Journal Article
Open access
Helen OnyeakaHelen Onyeaka
Helen Onyeaka
AAAdenike Akinsemolu
Adenike Akinsemolu
TMTaghi Miri
Taghi Miri
Nnabueze Darlington NnajiNnabueze Darlington Nnaji
Nnabueze Darlington Nnaji
KDKeru Duan
Keru Duan
CUChinenye Ugwa
Chinenye Ugwa

5 October 2022 in Journal of Molecular Liquids
Verified
Journal Article
Closed access
SGSoumya Ghosh
Soumya Ghosh
AOAmina Othmani
Amina Othmani
AMAlhadji Malloum
Alhadji Malloum
OCObileke Ke Christ
Obileke Ke Christ
HOHelen Onyeaka
Helen Onyeaka
SUSuhas
Suhas

27 June 2024 in Nutrients
Verified
Journal Article
Open access
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Helen OnyeakaHelen Onyeaka
Helen Onyeaka
Ovinuchi EjiohuoOvinuchi Ejiohuo
Ovinuchi Ejiohuo
OTOluseyi Rotimi Taiwo
Oluseyi Rotimi Taiwo
Nnabueze Darlington NnajiNnabueze Darlington Nnaji
Nnabueze Darlington Nnaji
OOOmowale A. Odeyemi
Omowale A. Odeyemi
Olumide OdeyemiOlumide Odeyemi
Olumide Odeyemi
Food insecurity, a multifaceted global challenge, intertwines with mental health concerns, necessitating nuanced strategies for sustainable solutions. The intricate web of challenges posed by these intersections has made it imperative to delineate a strategic way forward, incorporating solutions and robust policy recommendations. This study aims to comprehensively examine the intricate relationship between food security and its intersection with mental health on a global scale, offering insights into case studies, responses, and innovative approaches to inform effective strategies for addressing these pressing challenges. This study involved an analysis of a literature search, mainly between 2013 and 2023, with an updated addition of relevant 2024 studies. Examining responses across regions unveils varied interventions, from targeted social safety net programs in West Africa to technology-driven solutions in Asia. Success stories, such as Ghana’s sustainable agricultural practices and Canada’s income transfer programs, underscore the efficacy of multifaceted approaches. Innovative initiatives like community food programs offer promising alternatives to traditional food banks. Furthermore, international cooperation and policy innovations, exemplified by the European Union’s “Farm to Fork Strategy”, demonstrate the potential for collective action in addressing food insecurity. By prioritizing integrated strategies, global collaboration, and evidence-based policymaking, we lay the groundwork for sustainable development where communities thrive nutritionally and mentally. We emphasize continuous research and evaluation and incorporating mental health support into community programs to pave the way for a future where communities are not only food-secure but also mentally resilient.