Two-photon vapor cell-based optical clocks are strong candidates for next-generation portable atomic standards, offering simplicity, compactness, and high performance. Their narrow clock transitions with counter-propagating beams enable first-order Doppler-free operation. However, systematic perturbations such as the AC Stark shift, temperature-induced shift, and drifts resulting from the laser system pose challenges cause instabilities to medium- to long-term performance. This paper provides a comprehensive overview of Rb two-photon vapor cell optical standards, focusing on the long-term performance-limiting effects and potential mitigation strategies, aiming for clock stabilities better than 1 × 10⁻¹⁵ over the averaging time of a day and beyond.

Two-photon vapor cell based optical clocks are strong candidates for next-generation portable atomic standards, offering simplicity, compactness, and high performance. Their narrow clock transitions with counter-propagating beams enable first-order Doppler-free operation. However, systematic perturbations such as the AC Stark shift, temperature-induced shift, and drifts resulting from the laser system pose challenges, causing instabilities to the medium to long-term performances. This paper provides a comprehensive overview of Rb two-photon vapor cell optical standards, focusing on the long-term performance-limiting effects and potential mitigation strategies, aiming for the clock stabilities better than 1~$\times$~10$^{-15}$ over the averaging time of a day and beyond.