Dr. Desire Pantalone, Core Board and Responsible for "Studies on traumatic events and surgery" in the ESA-Topical Team on “Tissue Healing in Space: Techniques for promoting and monitoring tissue repair and regeneration” for Life Science Activities, is a general surgeon with interest in trauma surgery and emergency surgery and she is in staff of the Careggi University HospitalTrauma Team . She is also specialised in Vascular Surgery. She was Research Associate at the University of Chicago (IL) (Prof M. Michelassi) for Oncological Surgery and for Liver Transplantation and Hepatobiliary Surgery (Dr. J Emond). She is an instructor of the Advanced Trauma Operative Management (American College of Surgeons Committee for Trauma) and Fellow of the American College of Surgeons. She became an instructor for the ATOM course in Baltimore at the University of Maryland Shock Trauma Center. She is Professor and Tutor for Residents in General Surgery and Cardiac Surgery. Since 2008 participates in projects of the European Space Agency, as well as the Italian Space Agency. She is Author and Co-Author of these topics. His surgical activity is mainly emergency surgery, and trauma surgery but also open and laparoscopic surgical oncology. He attended the Robotic Surgery course and currently deals with Artificial Intelligence and Machine Learning for space and surgical applications. Another of her main interest is in the role of Damage Associated Molecular Patterns in Trauma patients.