Biomarkers are indispensable for precision medicine. However, focused single-biomarker development using human tissue has been complicated by sample spatial heterogeneity. To address this challenge, we tested a representation of primary tumor that synergistically integrated multiple in situ biomarkers of extracellular matrix from multiple sampling regions into an intratumor graph neural network. Surprisingly, the differential prognostic value of this computational model over its conventional non-graph counterpart approximated that of combined routine prognostic biomarkers (tumor size, nodal status, histologic grade, molecular subtype, etc.) for 995 breast cancer patients under a retrospective study. This large prognostic value, originated from implicit but interpretable regional interactions among the graphically integrated in situ biomarkers, would otherwise be lost if they were separately developed into single conventional (spatially homogenized) biomarkers. Our study demonstrates an alternative route to cancer prognosis by taping the regional interactions among existing biomarkers rather than developing novel biomarkers.

Traffic flow prediction significantly affects the intelligent transportation for digitized urban transportation management and urban traffic control. Considering the complexity and strong non-linearity shown by traffic flow data, the establishment of model regarding spatial correlations as well as time dynamics can remarkably help to accurately predict traffic flow. A lot of current methods are mainly focused on using the historical time series information of observations to extract sequence features. Such forecasting will cause the lack of information and lead to poor accuracy of the forecast results. Although some studies applied spatial-temporal information, but they are not very accurate. In network-based problems, we would consider the constraint of road networks. Specifically, intersection flows, road speed and travel time are related to road networks. Also, they restrict the long-term prediction of traffic flow. For addressing above issues, a graph multi-head attention neural network (GMHANN) is proposed for the purpose of traffic flow prediction. In design, the GMHANN has an encoder-decoder structure. By the encoder, the data are compressed into a hidden space representation, which, relying on the decoder, is reconstructed as output. Furthermore, we put forward a novel gated recurrent unit (GRU) module (AGRU) based on multi-head attention for the effective extraction of the spatial and temporal features exhibited by traffic flow data. Other state-of-the-art methods are employed for evaluating four public datasets, which reveals that our proposed method outperforms others.

With the development of artificial intelligence, speech recognition and prediction have become one of the important research domains with wild applications, such as intelligent control, education, individual identification, and emotion analysis. Chinese poetry reading contains rich features of continuous pronunciations, such as mood, emotion, rhythm schemes, lyric reading, and artistic expression. Therefore, the prediction of the pronunciation characteristics of a Chinese poetry reading is the significance for the presentation of high-level machine intelligence and has the potential to create a high-level intelligent system for teaching children to read Tang poetry. Mel frequency cepstral coefficient (MFCC) is currently used to present important speech features. Due to the complexity and high degree of nonlinearity in poetry reading, however, there is a tough challenge facing accurate pronunciation feature prediction, that is, how to model complex spatial correlations and time dynamics, such as rhyme schemes. As for many current methods, they ignore the spatial and temporal characteristics in MFCC presentation. In addition, these methods are subjected to certain limitations on prediction for long-term performance. In order to solve these problems, we propose a novel spatial-temporal graph model (STGM-MHA) based on multihead attention for the purpose of pronunciation feature prediction of Chinese poetry. The STGM-MHA is designed using an encoder-decoder structure. The encoder compresses the data into a hidden space representation, while the decoder reconstructs the hidden space representation as output. In the model, a novel gated recurrent unit (GRU) module (AGRU) based on multihead attention is proposed to extract the spatial and temporal features of MFCC data effectively. The evaluation comparison of our proposed model versus state-of-the-art methods in six datasets reveals the clear advantage of the proposed model.

Person tracking in hazardous goods factories can provide a significant improvement in security and safety. This article proposes a face verification model which can be used to record travel paths for staff or related persons in the factory. As face images are captured from the dynamic crowd at entrance–exit gates of workshops, face verification is challenged by polymorphic faces, poor illumination and changing of a person’s pose. To adapt to this situation, a new face verification model is proposed, which is composed of two advanced deep learning neural network models. Firstly, MTCNN (Multi-Task Cascaded Convolutional Neural Network) is used to construct a face detector. Based on the SphereFace-20 network model, we have reconstructed a convolutional network architecture with the embedded Batch Normalization elements and the optimized network parameters. The new model, which is called the MDCNN, is used to extract efficient face features. A set of specific processing algorithms is used in the model to process polymorphic face images. The multi-view faces and various types of face images are used to train the models. The experimental results have demonstrated that the proposed model outperforms most existing methods on benchmark datasets such as the Labeled Faces in the Wild (LFW) and YouTube Face (YTF) datasets without multi-view (accuracy is 99.38% and 94.30%, respectively) and the CNBC/FERET datasets with multi-view (accuracy is 94.69%).