Our group focus on non-coding RNAs (ncRNAs) in cancer and other diseases in the aging population. Since ncRNAs play important roles in the epigenetic regulation of gene expression at the transcriptional and post-transcriptional level, numerous ncRNAs are involved many diseases, such as cancer, cognitive impairment, and cardiovascular disease. Therefore, exploration of the biogenesis, the regulatory mechanisms, and the molecular activities of ncRNAs will deepen our understanding of the roles of ncRNAs in different diseases. Invention of new methods for the detection and delivery of ncRNAs will benefit the diagnosis and treatment of cancer and other diseases in the aging population.