Dr. Sílvia A. Macedo-Arantes
HERCULES Laboratory & IN2PAST Associate Laboratory, University of Évora, Évora, Portugal
Open to editorial collaborations, Special Issue guest editin...
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Academic Career Length
13Years (2014-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 January 2014 in Journal of Ethnopharmacology
Journal Article
M. Rosario MartinsSílvia A. Macedo-ArantesFCFátima Candeias
Fátima CandeiasMTMaria Teresa Tinoco
Maria Teresa TinocoJCJúlio Cruz-Morais
Júlio Cruz-Morais
9 March 2017 in Chemistry & Biodiversity
Journal Article
MVMaria Vieira
Maria Vieira
Lucinda J. BessaM. Rosario MartinsSílvia A. Macedo-ArantesATAntónio P. S. Teixeira
António P. S. TeixeiraABAnabela D. F. Belo
Anabela D. F. Belo +2
1 November 2019 in Food and Chemical Toxicology
Journal Article
Sílvia A. Macedo-ArantesAPAndreia Piçarra
Andreia Piçarra
MGMarisa Guerreiro
Marisa GuerreiroCSCátia Salvador
Cátia SalvadorFCFátima Candeias
Fátima Candeias
M. Rosario Martins +1
28 April 2016 in Planta Medica
Journal Article
Sílvia A. Macedo-ArantesFCFátima Candeias
Fátima CandeiasOLOrlando Lopes
Orlando Lopes
MLMónica Lima
Mónica Lima
MPMarízia Pereira
Marízia Pereira
M. Rosario Martins +2
The present study was carried out to evaluate the chemical and pharmacological properties of the essential oil of Lavandula stoechas subsp. luisieri, which is a spontaneous shrub widespread in Alentejo (Portugal). Oxygenated monoterpenes, such as 1,8-cineole, lavandulol, and necrodane derivatives, are the main components of essential oil. It revealed important antioxidant activity with a high ability to inhibit lipid peroxidation and showed an outstanding effect against a wide spectrum of microorganisms, such as gram-positive and gram-negative bacteria and pathogenic yeasts. The analgesic effect studied in rats was dose dependent, reaching a maximum of 67 % at 60 min with the dose of 200 mg/kg and the anti-inflammatory activity with this dose caused an inhibition in carrageenan-induced rat paw oedema (83 %) that is higher than dexamethasone 1 mg/Kg (69 %). Besides, animals exhibited normal behaviour after essential oil administration, revealing low toxicity. The essential oil of L. luisieri from Alentejo presents important pharmacological properties and low toxicity, and is a promised candidate to be used as a food supplement or in pharmaceutical applications.
11 January 2017 in Natural Product Research
Journal Article
Sílvia A. Macedo-ArantesAPAndreia Piçarra
Andreia PiçarraFCFátima Candeias
Fátima CandeiasDTDora Teixeira
Dora TeixeiraACA Teresa Caldeira
A Teresa CaldeiraM. Rosario MartinsEssential oils (EOs) and aqueous extracts of aerial parts of four aromatic species, Calamintha nepeta, Foeniculum vulgare, Mentha spicata and Thymus mastichina, from southwest of Portugal were characterised chemically and analysed in order to evaluate their antioxidant potential and cholinesterase inhibitory activities. The main components of EOs were oxygenated monoterpenes, and aqueous extracts were rich in phenol and flavonoid compounds. EOs and aqueous extracts presented a high antioxidant potential, with ability to protect the lipid substrate, free radical scavenging and iron reducing power. Furthermore, EOs and extracts showed AChE and BChE inhibitory activities higher than rivastigmine, the standard drug. Results suggested the potential use of EOs and aqueous extracts of these flavouring herbs as nutraceutical or pharmaceutical preparations to minimise the oxidative stress and the progression of degenerative diseases.
2 November 2021 in The European Physical Journal Plus
Journal Article
Sílvia A. Macedo-ArantesAPAndreia Piçarra
Andreia PiçarraACA Teresa Caldeira
A Teresa CaldeiraACAntónio candeias
António candeiasM. Rosario MartinsAbout Me
Dr. Sílvia A. Macedo-Arantes is an Invited Auxiliary Researcher at the HERCULES Laboratory & IN2PAST Associate Laboratory (University of Évora, Portugal). She holds a PhD in Biochemistry and researches the valorization of natural products, namely essential oils from aromatic plants of the Alentejo region. Her expertise focuses on the valorization and safeguarding of Natural and Cultural Heritage, combining material study, molecular biology, biochemistry, and microbiology to characterize biodeteriogenic agents and develop innovative solutions for heritage conservation. She has experience in the preparation and analysis of heritage samples and in the application of advanced analytical methodologies. Her career is marked by a strong interdisciplinary approach, linking the Chemistry of Natural Products to Microbiology and the Conservation of Cultural and Natural Heritage, and her trajectory reflects a resilient management of her scientific career with consistent scientific production of international impact. Currently, she is involved in international editorial activities and research projects aimed at the sustainable preservation of heritage materials and the discovery of new bioactive compounds with pharmacological potential.
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