Dr. Serhii Kropyvko
Functional Genomics, Institute of Molecular Biology and Genetics, Kyiv, Kyyiv, Misto, Ukraine
Senior Researcher
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Academic Career Length
19Years (2008-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 July 2015 in Cellular Signalling
Journal Article
TGTetyana Gryaznova
Tetyana GryaznovaSerhii KropyvkoMBMariia Burdyniuk
Mariia Burdyniuk
OGOlga Gubar
Olga GubarVKValentyna Kryklyva
Valentyna KryklyvaARAlla Rynditch
Alla Rynditch +1
1 August 2008 in Biochemical and Biophysical Research Communications
Journal Article
LTLiudmyla Tsyba
Liudmyla TsybaTGTetyana Gryaznova
Tetyana GryaznovaODOleksandr Dergai
Oleksandr Dergai
MDMykola Dergai
Mykola Dergai
Inessa SkrypkinaARAlla Rynditch
Alla Rynditch +4
1 May 2020 in Biocatalysis and Agricultural Biotechnology
Journal Article
ABAnastasiia Buziashvili
Anastasiia Buziashvili
LCLyubiv Cherednichenko
Lyubiv Cherednichenko
Serhii KropyvkoAYAlla Yemets
Alla Yemets
1 October 2018 in Gene
Journal Article
TGTetyana Gryaznova
Tetyana GryaznovaOGOlga Gubar
Olga GubarMBMariia Burdyniuk
Mariia Burdyniuk
Serhii KropyvkoARAlla Rynditch
Alla Rynditch24 September 2009 in Molecular Biology Reports
Journal Article
Serhii KropyvkoDGDmytro Gerasymchuk
Dmytro Gerasymchuk
Inessa SkrypkinaMDMykola Dergai
Mykola Dergai
ODOleksandr Dergai
Oleksandr Dergai
LTLiudmyla Tsyba
Liudmyla Tsyba +2
1 November 2015 in Biopolymers and Cell
Journal Article
Serhii KropyvkoTKS4 scaffold protein is involved in the formation of invadopodia, the production of reactive oxygen species (ROS) by tumor cells and other cellular processes. Aim. To identify new TKS4 partners involved in the actin cytoskeleton rearrangements and endo-/exocytosis. Methods. The GST pull-down assay was used to identify the interaction. Results. We revealed that TKS4 SH3 domains interact with the actin cytoskeleton reorganization proteins N-WASP and CR16, as well as with DNM2, SYNJ1 and OPHN1 which are involved in endo-/exocytosis. We also tested the WIP, WIRE, SHIP2, RhoU, RhoV and NUMB proteins, but their interaction with the SH3 domains of TKS4 was not found. Conclusions. The SH3 domains of TKS4 interact with N-WASP, DNM2, SYNJ1, OPHN1 and weakly with CR16 in vitro.\u
About Me
ADDRESS: Institute of Molecular Biology and Genetics (IMBG), National Academy of Sciences of Ukraine (NASU), 150 Zabolotnogo str., Kyiv 03143, Ukraine. s.v.kropyvko@edu.imbg.org.ua
EDUCATION AND DEGREES:
2006-2010 Obtained PhD degree in molecular biology at IMBG NASU.
2004-2006 Master in biology and biotechnology, Taras Shevchenko National University, Kyiv, Ukraine.
2000-2004 Bachelor in biology, Taras Shevchenko National University, Kyiv, Ukraine.
PROFESSIONAL TRAINING AND APPOINTMENT:
2019 – presently PhD, senior researcher of IMBG, NASU, Ukraine.
2017 –2019 Doctoral student, IMBG NASU, Ukraine.
2013 –2013 Short-Term Fellowship form the Boehringer Ingelheim Funds
(BIF), Institut de Cancérologie Gustave Roussy, UMR 8126,
Villejuif, France.
2012 FEBS Short-Term Fellowship, Institut de Cancérologie
Gustave Roussy, UMR 8126, Villejuif, France.
2010 –2017 research PhD, IMBG NASU, Ukraine.
2006 –2010 PhD student, IMBG NASU, Ukraine.
2002 –2006 research student, IMBG NASU, Ukraine.
2002 –2002 research student, Palladin Institute of Biochemistry NASU , Ukraine.
MAJOR RESEARCH INTERESTS:
The research is focused on the study of function and regulation expression of TKS proteins (TKS4 and TKS5), intersectins (ITSN1 and ITSN2) and verprolins (CR16, WIRE and WIP) protein families that encode scaffold proteins involved in actin cytoskeleton rearrangements, invasion, endocytosis and cell signaling.
MEMBERSHIP: FEBS (Ukrainian Biochemical Society)