My name is Shenzhao Lu. I investigate the genetic and molecular mechanisms underlying neurological diseases. I earned my Ph.D. in Neurobiology from the Institute of Neuroscience, Chinese Academy of Sciences. During my doctoral studies, I focused on the role of glia in neurodegeneration, identifying αB-crystallin as an inhibitor of glial autophagy in Parkinson’s disease and uncovering a novel signaling pathway involving 6-pyruvoyl-tetrahydropterin synthase (PTS) and astrocytic dopamine receptor D2 (DRD2), which contributes to neuroinflammation in Multiple Sclerosis. My current research focuses on identifying novel neurodevelopmental disease-associated genes, particularly those involved in actin cytoskeleton regulation in developmental epilepsy. My long-term goal is to advance our understanding of the cellular and molecular pathways underlying neurodevelopment and neurodegeneration.
Baylor College of Medicine
Houston, Texas, USA
Department of Molecular and Human Genetics
The NRI Zoghbi Scholar Award
Texas Children's Hospital
Finalist Award
Society of Chinese Bioscienctists in America, Texas Chapter, 2025 Annual Symposium
Post Doctoral Researcher
Baylor College of Medicine, Houston, USA
01 Jan 2020 - present