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Ms. So Yeon Sim
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Academic Career Length
2Years (2025-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
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Journal Article
Alcoholic hepatic steatosis (AHS) is a common early-stage symptom of liver disease caused by alcohol consumption. Accordingly, several aspects of AHS have been studied as potential preventive and therapeutic targets. In this study, a novel strategy was employed to inhibit fatty liver accumulation and counteract AHS through the consumption of microorganism-fermented Protaetia brevitarsis larvae (FPBs). By using an AHS rat model, we assessed the efficacy of FPB by examining the lipid profile of liver/serum and liver function tests to evaluate lipid metabolism modulation. After FPB administration, the lipid profile—including high-density lipoprotein, total cholesterol, and total triglycerides—and histopathological characteristics exhibited improvement in the animal model. Interestingly, AHS amelioration via FPBs administration was potentially associated with poly-γ-glutamic acid (PγG), which is produced by Bacillus species during fermentation. These findings support the formulation of novel natural remedies for AHS through non-clinical animal studies, suggesting that PγG-enriched FPBs are a potentially valuable ingredient for functional foods, providing an ameliorative effect on AHS.
About Me
I’m So-Yeon Sim, and I am currently majoring in Food Science and Biotechnology at Kyungpook National University. Graduated with a bachelor's degree in Biotechnology from Dong-A University in 2017 and completed a master's degree in the same field in 2019. Subsequently, completed doctoral coursework in Biomedical Life Sciences at Dong-A University in 2021. I worked as a researcher at the Yeongcheon Medicinal Plant Industry Support Center for one year and as a senior researcher at PhytoPharm for six months. Awarded the Best Post Award by The Korean Society of Food Preservation (2018), the Korean Society of Life Science (2019), and the Korean Society of Food Science and Nutrition (2023). Also received the Oral Presentation Award as a Doctoral Program Graduate from the Korean Society of Food Science and Nutrition in 2024. Holds certifications in various professional training programs, including the HACCP Team Course and GMP Training Course (2016), Competency Strengthening Training of R&D (2017), GCP Training Course (2018), Development and Application of Cosmeceutical Materials for Healthy Beauty (2018), and Engineer Food Processing (2020). I have published 5 domestic papers as the first author and 8 papers as a contributing author. I am very interested in research that investigates efficacy through microbiological testing, cell-based assays, and animal experiments, regardless of the material, and I am currently conducting such research.