Sofia Silva

Ms. Sofia Silva

University of Aveiro
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
28 July 2020 in Foods
Verified
Journal Article
Open access
PDF file
Cecilia Jiménez-LópezCecilia Jiménez-López
Cecilia Jiménez-López
Maria CarpenaMaria Carpena
Maria Carpena
Catarina Lourenço-LopesCatarina Lourenço-Lopes
Catarina Lourenço-Lopes
MGMaria Gallardo-Gomez
Maria Gallardo-Gomez
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
(1) Background: Extra virgin olive oil (EVOO) is responsible for a large part of many health benefits associated to Mediterranean diet as it is a fundamental ingredient of this diet. The peculiarities of this golden, highly valued product are in part due to the requirements that must be met to achieve this title, namely, it has to be obtained using exclusively mechanical procedures, its free acidity cannot be greater than 0.8%, it must not show sensory defects, and it has to possess a fruity taste. (2) Methods: All these characteristics are key factors to EVOO quality, thus the chemical composition of these many health-promoting compounds, such as unsaturated fatty acids (which are also the major compounds, especially oleic acid), as well as minor components such as tocopherols or phenolic compounds (which behave as natural antioxidants) must be preserved. (3) Results: Due to the presence of all these compounds, the daily consumption of EVOO entails health benefits such as cardioprotective, antioxidant, anti-inflammatory, anti-tumor properties or acting as regulator of the intestinal microbiota, among others. (4) Conclusions: Taking all together, conserving EVOO chemical composition is essential to preserve its properties, so it is worth to control certain factors during storage like exposure to light, temperature, oxygen presence or the chosen packaging material, to maintain its quality and extend its shelf-life until its consumption.

27 March 2021 in Marine Drugs
Verified
Journal Article
Open access
PDF file
APAntía Pereira
Antía Pereira
Paz OteroPaz Otero
Paz Otero
Javier Echave ÁlvarezJavier Echave Álvarez
Javier Echave Álvarez
ACAnxo Carreira-Casais
Anxo Carreira-Casais
Franklin ChamorroFranklin Chamorro
Franklin Chamorro
Miguel Angel Prieto LageMiguel Angel Prieto Lage
Miguel Angel Prieto Lage
Algae are considered pigment-producing organisms. The function of these compounds in algae is to carry out photosynthesis. They have a great variety of pigments, which can be classified into three large groups: chlorophylls, carotenoids, and phycobilins. Within the carotenoids are xanthophylls. Xanthophylls (fucoxanthin, astaxanthin, lutein, zeaxanthin, and β-cryptoxanthin) are a type of carotenoids with anti-tumor and anti-inflammatory activities, due to their chemical structure rich in double bonds that provides them with antioxidant properties. In this context, xanthophylls can protect other molecules from oxidative stress by turning off singlet oxygen damage through various mechanisms. Based on clinical studies, this review shows the available information concerning the bioactivity and biological effects of the main xanthophylls present in algae. In addition, the algae with the highest production rate of the different compounds of interest were studied. It was observed that fucoxanthin is obtained mainly from the brown seaweeds Laminaria japonica, Undaria pinnatifida, Hizikia fusiformis, Sargassum spp., and Fucus spp. The main sources of astaxanthin are the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp. Lutein and zeaxanthin are mainly found in algal species such as Scenedesmus spp., Chlorella spp., Rhodophyta spp., or Spirulina spp. However, the extraction and purification processes of xanthophylls from algae need to be standardized to facilitate their commercialization. Finally, we assessed factors that determine the bioavailability and bioaccesibility of these molecules. We also suggested techniques that increase xanthophyll’s bioavailability.

30 January 2020 in Molecules
Verified
Journal Article
Open access
PDF file
MFMaria Fraga-Corral
Maria Fraga-Corral
PGPaula Garcia-Oliveira
Paula Garcia-Oliveira
APAntía Pereira
Antía Pereira
Catarina Lourenço-LopesCatarina Lourenço-Lopes
Catarina Lourenço-Lopes
Cecilia Jiménez-LópezCecilia Jiménez-López
Cecilia Jiménez-López
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
Tannins are polyphenolic compounds naturally found in vegetables. Their presence in nature has prompted their historical use in many different ways. The revision of their traditional utilization has allowed their further modification aiming for an industrial application. Sometimes these modifications have implied the addition of harmful substances such as formaldehyde, classified as a carcinogen of category B1. In other cases, these natural tannins have been replaced by synthetic compounds that threaten human and animal health and damage the environment. Therefore, currently, both academy and industry are searching for the substitution of these unsafe complexes by the increasing inclusion of tannins, natural molecules that can be obtained from several and diverse renewable resources, modified using harmless additives. To achieve promising results, cost-efficient and eco-friendly extraction methods have been designed. Once these green alternatives have been isolated, they have been successfully applied to many fields with very assorted aims of utilization such as coagulants, adhesives, floatation agents, tannings, dyes, additives, or biomolecules. Therefore, this review offers a global vision of the full process that involves the tannin’s technological application including an overview of the most relevant tannin sources, effective extraction methods, and their utilization in very diverse fields.

12 May 2020 in Food & Function
Verified
Journal Article
Closed access
PDF file
Cecilia Jiménez-LópezCecilia Jiménez-López
Cecilia Jiménez-López
MFMaria Fraga-Corral
Maria Fraga-Corral
Maria CarpenaMaria Carpena
Maria Carpena
PGPaula Garcia-Oliveira
Paula Garcia-Oliveira
Javier Echave ÁlvarezJavier Echave Álvarez
Javier Echave Álvarez
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
Agro-food industrial waste is currently being accumulated, pushing scientists to find recovery strategies to obtain bioactive compounds within a circular bioeconomy. Target phenolic compounds have shown market potential by means of optimization extraction techniques.

25 September 2020 in Antibiotics
Verified
Journal Article
Open access
PDF file
Aurora SilvaAurora Silva
Aurora Silva
Sofia SilvaSofia Silva
Sofia Silva
Maria CarpenaMaria Carpena
Maria Carpena
PGPaula Garcia-Oliveira
Paula Garcia-Oliveira
PEPatricia Gullón Estévez
Patricia Gullón Estévez
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
In the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.

26 January 2021 in Foods
Verified
Journal Article
Open access
PDF file
MFMaria Fraga-Corral
Maria Fraga-Corral
Paz OteroPaz Otero
Paz Otero
Lucia CassaniLucia Cassani
Lucia Cassani
Javier Echave ÁlvarezJavier Echave Álvarez
Javier Echave Álvarez
PGPaula Garcia-Oliveira
Paula Garcia-Oliveira
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
Tannins are polyphenolic compounds historically utilized in textile and adhesive industries, but also in traditional human and animal medicines or foodstuffs. Since 20th-century, advances in analytical chemistry have allowed disclosure of the chemical nature of these molecules. The chemical profile of extracts obtained from previously selected species was investigated to try to establish a bridge between traditional background and scientific data. The study of the chemical composition of these extracts has permitted us to correlate the presence of tannins and other related molecules with the effectiveness of their apparent uses. The revision of traditional knowledge paired with scientific evidence may provide a supporting background on their use and the basis for developing innovative pharmacology and food applications based on formulations using natural sources of tannins. This traditional-scientific approach can result useful due to the raising consumers’ demand for natural products in markets, to which tannin-rich extracts may pose an attractive alternative. Therefore, it is of interest to back traditional applications with accurate data while meeting consumer’s acceptance. In this review, several species known to contain high amounts of tannins have been selected as a starting point to establish a correlation between their alleged traditional use, tannins content and composition and potential bioaccessibility.