The study presents a concise overview on the main effects on satellites due to space weather drivers compared to the well-known interplanetary, magnetospheric and ground-based consequences. The solar-activity-driven influences include specific physics-based effects on the spacecraft surface and on-board electronics due to electromagnetic emission and energetic particles as well as complex effects due to geomagnetic storms which may endanger the mission performance and spacecraft longevity. We select as test examples the Starlink satellites in the period 2019–2022 and present the temporal correspondence between their launches and the space weather phenomena. Based on comparative analysis, we discuss whether the occurrence vs. the intensity of solar and interplanetary drivers of space weather can be considered as a cause for orbital stability problems and satellite loss. The results suggest that a sequence of geomagnetic disturbances together with multiple weak space weather events could lead to severe levels of atmospheric drag ending in a service or satellite loss.