Water is essential for ecological balance, environmental sustainability, and food security, particularly in arid regions where effective water management increasingly depends on farmer cooperation. The Samarkand region of Uzbekistan, known for its favorable climate and leading role in grape production, is facing rising drought conditions. This study explores the factors influencing grape farmers’ willingness to collaborate on water management in the districts of Ishtikhan, Payarik, and Kushrabot, which together produce 75–80% of the region’s grapes. A quantitative survey of 384 grape-producing households was conducted across 19 county citizens’ gatherings (38.7% of such gatherings), and structural equation modeling was employed to analyze a framework consisting of four dimensions: norms, environmental concerns, economic barriers, and the intention to adopt sustainable practices. The results indicate that norms and environmental concerns positively influence collaboration, suggesting a collective orientation toward sustainability. In contrast, economic barriers such as high costs and limited financial capacity significantly hinder cooperative behavior. Furthermore, a strong individual intention to adopt sustainable practices was associated with a greater likelihood of collaboration. These findings highlight the critical drivers and constraints shaping collective water use in agriculture and suggest that targeted policy measures and community-led efforts are vital for promoting sustainable water governance in drought-prone regions.