Three series of novel fused nitrogen heterocyclic systems such as 1,2,4-triazolo[1,5-α ] pyridines (5-7 and 9), pyrido[1,2-b][1,2,4]triazines (10, 11, 13 and 15), and pyrido[1,2-b][1,2,4]triazepines (17, 18, 20 and 22) linked with a chromone moiety were synthesized from the key intermediate 1,6-diamino-(6-chloro-4-oxo-4H-chromen-3-yl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (4) with some electrophilic reagents. The structures of the novel compounds were established by elemental analyses and spectral data. All the products were also screened invitro for their antimicrobial activity. Compounds 7, 9 and 15 showed the highest activities when compared with the reference drugs.

New and stable coordinated compounds have been isolated in a good yield. The chelates have been prepared by mixing Co(II), Ni(II), Cu(II), and Cd(II) metal ions with (1E)-1-((6-methyl-4-oxo-4H-chromen-3-yl)methylene)thiocarbonohydrazide (MCMT) in 2 : 1 stoichiometry (MCMT : M²⁺). Various techniques, including elemental microanalyses, molar conductance, thermal studies, FT-IR, ¹H-NMR, UV-Vis, and XRD spectral analyses, magnetic moment measurements, and electrical conductivity, were applied for the structural and spectroscopic elucidation of the coordinating compounds. Further, computational studies using the DFT-B3LYP method were reported for MCMT and its metal complexes. MCMT behaves as a neutral NS bidentate moiety that forms octahedral complexes with general formula [M(MCMT)₂Cl(OH₂)]Cl·XH₂O (M = Cu²⁺; (X = ½), Ni²⁺, Co²⁺; (X = 1)); [Cd(MCMT)₂Cl₂]·½H₂O. There is good confirmation between experimental infrared spectral data and theoretical DFT-B3LYP computational outcomes where MCMT acts as a five-membered chelate bonded to the metal ion through azomethine nitrogen and thiocarbonyl sulphur donors. The thermal analysis is studied to confirm the elucidated structure of the complexes. Also, the kinetic and thermodynamic parameters of the thermal decomposition steps were evaluated. The measured optical band gap values of the prepared compounds exhibited semiconducting nature. AC conductivity and dielectric properties of the ligand and its complexes were examined, which showed that Cu(II) complex has the highest dielectric constant referring to its high polarization and storage ability.

This study is the first to investigate the physical properties of ruthenium-based hydride perovskites, specifically XRuH₃ (where X = Cr, V, Ni). There is currently no existing literature on these compounds.