COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are critical concerns about their adverse effects on human health. This study aims to assess the health effects of sanitizers and disinfectants on a global scale. A total of 91,056 participants from 154 countries participated in this cross-sectional study. Information on the use of sanitizers and disinfectants and health was collected using an electronic questionnaire, which was translated into 26 languages via web-based platforms. The findings of this study suggest that detergents, alcohol-based substances, and chlorinated compounds emerged as the most prevalent chemical agents compared to other sanitizers and disinfectants examined. Most frequently reported health issues include skin effects and respiratory effects. The Chi-square test showed a significant association between chlorinated compounds (sodium hypochlorite and per-chlorine) with all possible health effects under investigation (p-value <0.001). Examination of risk factors based on multivariate logistic regression analysis showed that alcohols and alcohols-based materials were associated with skin effects (OR, 1.98; 95%CI, 1.87–2.09), per-chlorine was associated with eye effects (OR, 1.83; 95%CI, 1.74–1.93), and highly likely with itching and throat irritation (OR, 2.00; 95%CI, 1.90–2.11). Furthermore, formaldehyde was associated with a higher prevalence of neurological effects (OR, 2.17; 95%CI, 1.92–2.44). Furthermore, formaldehyde was associated with a higher prevalence of neurological effects (OR, 2.17; 95%CI, 1.92–2.44). The use of sodium hypochlorite and per-chlorine also had a high chance of having respiratory effects. The findings of the current study suggest that health authorities need to implement more awareness programs about the side effects of using sanitizers and disinfectants during viral epidemics especially when they are used or overused.

Background: Burnout is a common occupational health risk among healthcare professionals. While the phenomenon has been studied in physicians and nurses, limited evidence exists regarding pharmacists and public health inspectors despite their critical role in ensuring safe medication use and protecting population health. The study aims to identify and analyze the influence of work environment characteristics on the level of professional burnout among master pharmacists, assistant pharmacists, and public health inspectors. Methods: A cross-sectional anonymous survey was conducted among 491 healthcare professionals (221 master pharmacists, 151 assistant pharmacists, and 119 public health inspectors). Burnout was assessed using the validated Maslach Burnout Inventory–Human Services Survey (MBI-HSS (MP)), covering three dimensions: emotional exhaustion (EE), depersonalization (DP), and personal accomplishment (PA). Work environment characteristics were examined across four domains: work tasks, stressors, occupational risks, and social environment. Data were analyzed using descriptive statistics and chi-square tests with IBM SPSS. Results: High levels of EE (66.6%) and DP (53%) were reported, while low PA was less frequent (6.7%). Significant factors associated with EE included time constraints (χ² = 9.985; p < 0.01), workflow disruptions (χ² = 23.987; p < 0.001), insufficient information (χ² = 22.890; p < 0.001), and lack of recognition (χ² = 16.498; p < 0.001). The social environment demonstrated the broadest impact, influencing all three burnout dimensions. Conclusions: The study found a risk of professional burnout among the surveyed groups which is associated with modifiable work environment characteristics. Preventive interventions aimed at promoting a supportive work environment could help mitigate this risk.

Use of assessment scales for early detection of the risk of reduced work ability in mental work