Tian-Wei Liang

Dr. Tian-Wei Liang

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Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 September 2022 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
TLTian-Wei Liang
Tian-Wei Liang
ZQZhuyun Qian
Zhuyun Qian
Yong TaoYong Tao
Yong Tao
YPYaguang Peng
Yaguang Peng
YCYanhui Cui
Yanhui Cui
NLNingdong Li
Ningdong Li
Purpose: To analyze the relationship between the severity of type 1 retinopathy of prematurity (ROP) and the level of vascular endothelial growth factor (VEGF) in aqueous fluid. Methods: The aqueous VEGF levels of 49 patients (88 eyes) with type 1 ROP were retrospectively analyzed. These eyes were categorized into three groups according to the severity of disease: aggressive retinopathy of prematurity (A-ROP), threshold of ROP (T-ROP), and type 1 pre-threshold ROP (P-T-1). The differences in aqueous VEGF levels among these three groups were compared. The relationship between the aqueous VEGF level and the retinal changes of ROP, including the vessel tortuosity in zone I, and the location and stage of the ROP lesions, were also analyzed. Results: The aqueous VEGF level of the A-ROP group was the highest among the three groups, followed by those of the T-ROP and P-T-1 groups. The aqueous VEGF level was negatively correlated with the zone and the stage of the ROP diseases, while it was positively correlated with the venous tortuosity in zone I and had no relevance with the artery tortuosity in zone I. Conclusions: The aqueous VEGF level in A-ROP was the highest in type I ROP. The location of the ROP lesions and the venous tortuosity in zone I correlated with the aqueous VEGF level and could indicate the severity of ROP.
10 December 2022 in American Journal of Ophthalmology
Verified
Journal Article
Closed access
MHMan Hu
Man Hu
TLTian-Wei Liang
Tian-Wei Liang
FLFei Leng
Fei Leng
BZBin Zhang
Bin Zhang
YXYong-li Xu
Yong-li Xu
HWHuaizhou Wang
Huaizhou Wang
10 October 2024 in Preprints.org
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Preprint
Open access
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TLTian-Wei Liang
Tian-Wei Liang
YCYan Hui Cui
Yan Hui Cui
MHMan Hu
Man Hu
DCDi Cao
Di Cao
HYHonggai Yan
Honggai Yan
LLLi Li
Li Li
Introduction: To describe a case of unilateral exudative retinal detachment and severe uveitis with a large subretinal deposit in a 6-year-old girl presenting with left thigh lymphadenitis. Case Presentation: A metagenome next-generation sequencing (mNGS) of the vitreous body was performed, revealing Bartonella henselae. The patient showed the resolution of retinal detachment and uveitis, as well as improvement of left thigh lymphadenitis, in response to systemic and ocular antibiotics and corticosteroids. Conclusion: Bartonella henselae neuroretinitis may manifest as exudative retinal detachment with extensive subretinal lesions and uveitis. The treatment involving systemic and ocular antibiotics and corticosteroids proved to be effective.
9 December 2024 in Diagnostics
Verified
Journal Article
Open access
PDF file
TLTian-Wei Liang
Tian-Wei Liang
YCYanhui Cui
Yanhui Cui
MHMan Hu
Man Hu
DCDi Cao
Di Cao
HYHonggai Yan
Honggai Yan
LLLi Li
Li Li
Bartonella henselae is a Gram-negative bacillus, mainly parasitizing on cats. When a child is scratched by a cat, they may present with the disease symptoms including regional lymphadenopathy, malaise, fever, and splenomegaly, which is known as cat-scratch disease (CSD). Ocular manifestations occur in 5–10% of patients with CSD. Neuroretinitis is the most common, and, in addition, Parinaud oculoglandular syndrome, endophthalmitis, retinochoroiditis, vascular occlusions, multiple mass-like lesions resembling ocular metastases, serous macular detachments, and retinal vasoproliferative lesions may also occur. We report a case of unilateral exudative retinal detachment and uveitis with a large subretinal deposit on the macula in a 6-year-old female with CSD, along with lymphadenitis on her left thigh. To the best of our knowledge, this case of exudative retinal detachment and uveitis with a large subretinal deposit under the retina affecting the macular area above the optic disc has not been previously reported.