Acacia seyal is an important source of gum Arabic. The availability, traditional, medicinal, pharmaceutical, nutritional, and cosmetic applications of gum acacia have pronounced its high economic value and attracted global attention. In addition to summarizing the inventions/patents applications related to gum A. seyal, the present review highlights recent updates regarding its phytoconstituents. Traditional, cosmetic, pharmaceutical, and medicinal uses with the possible mechanism of actions have been also reviewed. The patent search revealed the identification of 30 patents/patent applications of A. seyal. The first patent related to A. seyal was published in 1892, which was related to its use in the prophylaxis/treatment of kidney and bladder affections. The use of A. seyal to treat cancer and osteoporosis has also been patented. Some inventions provided compositions and formulations containing A. seyal or its ingredients for pharmaceutical and medical applications. The inventions related to agricultural applications, food industry, cosmetics, quality control of gum Arabic, and isolation of some chemical constituents (L-rhamnose and arabinose) from A. seyal have also been summarized. The identification of only 30 patents/patent applications from 1892 to 15 November 2021 indicates a steadily growing interest and encourages developing more inventions related to A. seyal. The authors recommend exploring these opportunities for the benefit of society.

Eating disorders (ED) are one of the most common psychiatric problems faced by todays adolescent girls where the attitude towards weight and shape as well as their perception of body shape are disturbed. The aim of the paper is to assess the prevalence and associated factors of disordered eating attitudes among adolescent girls of Arar city, Kingdom of Saudi Arabia. This is a cross-sectional survey design in which 314 adolescents females (age: 15-19 years) were selected from four schools of Arar city, KSA. Subjects were asked to fill pre-tested questionnaire about socioeconomic status, eating habits and Eating attitude test 26 (EAT 26), there height and weight were measured and BMI was calculated. Disturbed eating behaviors (EAT-26>20) was found in 25.47% participants. The prevalence of disordered eating was more in overweight and obese than normal weight. Vegetarian girls had higher EAT 26 score than non - vegetarian and significant difference was found in total EAT 26 score and subgroup namely oral control and dieting score (P<0.01) but non-significant difference was found between Saudi and non-Saudi adolescent girls in different BMI ranges. Eating disorders prevalent in adolescent girls and were strongly associated with weight status and eating habits. Future prospective and experimental studies are warranted to advance our understanding of the risk factors to enable better preventive program planning.

Selenium is an indispensable trace element for all living organisms. It is an essential structural component of several selenium-dependent enzymes, which support the human body’s defense mechanism. Recently, the significance of selenium in preventing/treating COVID-19 has been documented in the literature. This review highlights the clinical studies, compositions, and patent literature on selenium to prevent/treat COVID-19. Selenium exerts its anti-COVID-19 action by reducing oxidative stress, declining the expression of the ACE-2 receptor, lowering the discharge of pro-inflammatory substances, and inhibiting the 3CL_Pro (main protease) and PL_pro enzyme of SARS-CoV-2. The data of clinical studies, inventive compositions, and patent literature revealed that selenium monotherapy and its compositions with other nutritional supplements/drugs (vitamin, iron, zinc, copper, ferulic acid, resveratrol, spirulina, N-acetylcysteine, fish oil, many herbs, doxycycline, azithromycin, curcumin, quercetin, etc.,) might be practical to prevent/treat COVID-19. The studies have also suggested a correlation between COVID-19 and selenium deficiency. This indicates that adequate selenium supplementation may provide promising treatment outcomes in COVID-19 patients. The authors foresee the development and commercialization of Selenium-based compositions and dosage forms (spray, inhalers, control release dosage forms, etc.) to battle COVID-19. We also trust that numerous selenium-based compositions are yet to be explored. Accordingly, there is good scope for scientists to work on developing novel and inventive selenium-based compositions to fight against COVID-19. However, there is also a need to consider the narrow therapeutic window and chemical interaction of selenium before developing selenium-based compositions.

Zinc is an essential nutrient for human health; it is involved in the catalytic, structural, and regulatory functions of the human cellular system. Different compositions of zinc, as well as its pharmaceutically acceptable salts, are available on the market. Recent studies have demonstrated the role of zinc in combating COVID-19. It has been determined that zinc prevents the entry of SARS-CoV-2 into cells by lowering the expression of ACE-2 receptors and inhibiting the RNA-dependent RNA polymerase of SARS-CoV-2. Zinc also prevents the cytokine storm that takes place after the entry of SARS-CoV-2 into the cell, via its anti-inflammatory activity. The authors believe that no study has yet been published that has reviewed the trends, inventions, and patent literature of zinc compositions to treat/prevent COVID-19. Accordingly, this review has been written in order to fill this gap in the literature. The information about the clinical studies and the published patents/patent applications was retrieved from different databases. This review covers patent literature on zinc compositions up to 31 January 2022. Many important patents/patent applications for zinc-based compositions filed by innovative universities and industries were identified. The patent literature revealed zinc compositions in combination with zinc ionophores, antioxidants, antivirals, antibiotics, hydroxychloroquine, heparin, ivermectin, and copper. Most of these studies were supported by clinical trials. The patent literature supports the potential of zinc and its pharmaceutical compositions as possible treatments for COVID-19. The authors believe that countless zinc-based compositions are still unexplored, and there is an immense opportunity to evaluate a considerable number of the zinc-based compositions for use against COVID-19.

Disordered Eating Attitude and Body Dissatisfaction among Adolescents of Arab Countries: A Review

A cross-sectional study among 701 school children (12-16 years) was conducted in Aligarh to find out the prevalence of hypertension and to correlate school going adolescent's blood pressure with age, sex, height and weight. The weight was taken by a standardized weighing machine while height was measured using a standard stediometer. Blood pressure measurements were taken by a mercury sphygmomanometer. The distribution of blood pressure by anthropometric characteristics were studied. Mean, standard deviation and correlation coefficient were used for statistical analysis. The overall prevalence of hypertension was found to be 9.4%. Blood pressure of both gender appear to have positive correlation with anthropometric characteristics. Study recommends that children must be screened regularly for blood pressure so that remedial measure can be initiated as early as possible.