The WHO estimates that, with the development of urbanization, 25% of the population is suffering from psychological and mental distress. Preliminary evidence has suggested that aquatic environments and riparian areas, i.e., waterscapes, can benefit psychological and mental wellbeing. The aim of this study was to identify the processes of waterscape psychological and mental health promotion through aliterature review. We propose a design framework of waterscapes for achieving psychological and mental health in the general population that often visits waterscapes, which has the function of therapeutic landscapes through values of accessibility, versatility, habitats, and biodiversity. According to theories, waterscapes can improve psychological and mental health to divert negative emotions through mitigation (e.g., reduced urban heat island), instoration (e.g., physical activity and state of nature connectedness), and restoration (e.g., reduced anxiety/attentional fatigue). By accessing water (e.g., streams, rivers, lakes, wetlands, and the coast) and riparian areas, people can get in close contact with nature and spend more time in activities (e.g., walking, exploring, talking, and relaxing). Waterscapes with healing effects can enhance psychological resilience to promote people’s psychological and mental health. Future research should focus on ensuring an adequate supply of waterscapes and promoting the efficiency of waterscape ecosystem services on mental health. Moreover, fora deep understanding of the complexity of nature–human health associations, it is necessary to explore more consistent evidence for therapeutic waterscapes considering the characteristics and functional mechanisms of waterscape quality, in terms of freshness, luminescence, rippling or fluidity, and cultural value, to benefit public health and biodiversity conservation.

With the fast pace of global urbanization, anthropogenic disturbances not only lead to frequent disasters, but also cause direct and indirect ecological and economic losses. To reduce the adverse effects of anthropogenic disturbances as part of sustainable ecosystem management, assessments of habitat quality and ecological risk are necessary. The objectives of this study are to analyze environmental conditions of the Beijing-Hangzhou Grand Canal (Suzhou section) for evaluating habitat quality and habitat degradation, and to conduct ecological-risk early warning assessment in this section. The Grand Canal is the longest and first canal in the world to be artificially excavated from natural rivers and lakes. By evaluating habitat quality using the InVEST suite of open-source software models for mapping and valuing the ecosystem, it was found that the natural lands with high habitat quality such as wetlands, forests and lakes along the Suzhou section of the Grand Canal have gradually decreased, while construction lands such as roads and buildings have gradually increased; there is a clear trend of decreasing areas with high habitat quality and increasing areas with low habitat quality, which is likely the result of urbanization. It was also found that the region has a high habitat degradation index, meaning that areas located at the junction of different land types are vulnerable to the surrounding environment due to narrow buffer zones that allow areas with high habitat quality to be easily affected by areas with low habitat quality. In terms of ecological risks, it was found that the natural land area with high habitat quality in the downstream locations was declining, thereby increasing the risks of pollution and flooding events while reducing the ecosystem’s resilience. The valuation model used in this study can be used as an effective decision-support tool to prioritize important ecological areas for conservation in the Grand Canal, and can also be adapted for use in the ecosystem management of other regions.

D-Allulose has become a promising alternative sweetener due to its unique properties of low caloric content, moderate sweetness, and physiological effects. D-Allulose 3-epimerase (DAEase) is a promising enzyme for D-Allulose production. However, the low catalytic efficiency limited its large-scale industrial applications. To obtain a more effective biocatalyst, a putative DAEase from Christensenellaceae bacterium (CbDAE) was identified and characterized. The recombinant CbDAE exhibited optimum activity at pH 7.5°C and 55°C, retaining more than 60% relative activity from 40°C to 70°C, and the catalytic activity could be significantly increased by Co²⁺ supplementation. These enzymatic properties of purified CbDAE were compared with other DAEases. CbDAE was also found to possess desirable thermal stability at 55°C with a half-life of 12.4 h. CbDAE performed the highest relative activity towards D-allulose and strong affinity for D-fructose but relatively low catalytic efficiency towards D-fructose. Based on the structure-guided design, the best double-mutation variant G36N/W112E was obtained which reached up to 4.21-fold enhancement of catalytic activity compared with wild-type (WT) CbDAE. The catalytic production of G36N/W112E with 500 g/L D-fructose was at a medium to a higher level among the DAEases in 3.5 h, reducing 40% catalytic reaction time compared to the WT CbDAE. In addition, the G36N/W112E variant was also applied in honey and apple juice for D-allulose conversion. Our research offers an extra biocatalyst for D-allulose production, and the comprehensive report of this enzyme makes it potentially interesting for industrial applications and will aid the development of industrial biocatalysts for D-allulose.