Yiyou Gu, Ph.D., is a biomedical researcher at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. His research focuses on the pathogenesis of mucormycosis, a life-threatening invasive fungal infection, with an emphasis on fungal virulence, host–pathogen interactions, and the development of novel therapeutic and diagnostic strategies. His work investigates the molecular mechanisms of fungal invasion, host receptor signaling, innate immune responses, and vascular injury. He has contributed to the development of a humanized monoclonal antibody targeting the fungal invasin CotH, work published in Science Translational Medicine, and to rapid molecular diagnostic approaches for mucormycosis. His current research integrates molecular biology, host–pathogen studies, animal models, and translational approaches to identify new strategies for combating invasive fungal infections. Dr. Gu received his training in molecular biology and gene regulation and developed short tandem target mimic (STTM) technology for microRNA functional studies during his Ph.D. His long-term goal is to translate fundamental discoveries in fungal pathogenesis into improved diagnostics and therapies for invasive fungal diseases.
The Lundquist Institute
Torrance, California, USA
Department of Medcine
Senior Scientist or Principal Investigator
The Lundquist Institute, Torrance, USA
01 Aug 2026 - present
Manager
Vitalex Biosciences, Torrance, USA
01 Jan 2022 - present
Research or Laboratory Scientist
The Lundquist Institute, Torrance, USA
01 Jul 2022 - 31 Jul 2026
Post Doctoral Researcher
The Lundquist Institute, Torrance, USA
01 Aug 2017 - 30 Jun 2022