Dr. Antonio Mirijello
Casa Sollievo della Sofferenza Hospital IRCCS
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Academic Career Length
21Years (2006-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 December 2020 in JACC
Journal Article
GRGregory A. Roth
Gregory A. RothGMGeorge A. Mensah
George A. MensahCJCatherine O. Johnson
Catherine O. Johnson
GAGiovanni Addolorato
Giovanni Addolorato
EAEnrico Ammirati
Enrico Ammirati
CMChristopher J.L. Murray
Christopher J.L. Murray
+626
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019.
1 December 2007 in The Lancet
Journal Article
GAGiovanni Addolorato
Giovanni AddoloratoLLLorenzo Leggio
Lorenzo Leggio
AFAnna Ferrulli
Anna FerrulliSCSilvia Cardone
Silvia Cardone
LVLuisa Vonghia
Luisa VonghiaGGGiovanni Gasbarrini
Giovanni Gasbarrini
+6
11 April 2013 in Alcohol, Clinical and Experimental Research
Journal Article
GAGiovanni Addolorato
Giovanni AddoloratoAntonio MirijelloLLLorenzo Leggio
Lorenzo Leggio
AFAnna Ferrulli
Anna FerrulliCDCristina D'ANgelo
Cristina D'ANgelo
GGGemelli OLT Group
Gemelli OLT Group
+6
1 September 2016 in Journal of Hepatology
Journal Article
GAGiovanni Addolorato
Giovanni AddoloratoAntonio MirijelloPBPablo Barrio
Pablo Barrio
Antoni Gual10 February 2015 in Drugs
Journal Article
Antonio MirijelloCDCristina D’aNgelo
Cristina D’aNgelo
AFAnna Ferrulli
Anna FerrulliGVGabriele Vassallo
Gabriele VassalloMAMariangela Antonelli
Mariangela Antonelli
GAGiovanni Addolorato
Giovanni Addolorato +3
17 March 2011 in Alcohol and Alcoholism
Journal Article
GAGiovanni Addolorato
Giovanni AddoloratoLLLorenzo Leggio
Lorenzo Leggio
AFAnna Ferrulli
Anna FerrulliSCSilvia Cardone
Silvia Cardone
GBGiorgio Bedogni
Giorgio BedogniNNN. Nicotra
N. Nicotra
+22
Aims: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence. Methods: We present a secondary analysis of a 12-week double-blind, placebo-controlled, randomized clinical trial with two doses of baclofen, specifically 10 mg t.i.d. and 20 mg t.i.d. Out of 94 subjects consecutively screened, 42 were randomized into the study. Fourteen of the 42 patients were randomly allocated to placebo, 14 to the group treated with baclofen 10 mg t.i.d. (B10 mg) and 14 to the group treated with baclofen 20 mg t.i.d. (B20 mg). Results: Compared with patients allocated to placebo, patients allocated to the B10 mg group had a 53% reduction in the number of drinks per day (P < 0.0001) and patients allocated to the B20 mg group had a 68% reduction in the number of drinks per day (P < 0.0001), with respect to the number of drinks per day during the 28 days before randomization. The effect of baclofen 20 mg t.i.d. was greater than that of baclofen 10 mg t.i.d. (P = 0.0214, Wald test) showing a dose–effect relationship. Both doses of baclofen were well tolerated. Conclusion: This is provisional evidence of a dose–response effect for baclofen in the treatment of alcohol dependence.
About Me
2006: M.D. degree cum laude at Catholic University, Rome, IT.
2012: Internal Medicine Residency, same university.
2013: Echography M.Sc., Sapienza University, Rome, IT.
2012 to 2014: Internal Medicine consultant, “A. Gemelli” University Hospital, Rome .
2015 to 2016: Emergency Department, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, IT.
From 2017: Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, IT.
2004 to present: Member of the Alcohol Use Disorders Unit (director Prof. Giovanni Addolorato), participating in several multicenter studies, published in top-ranking journals (i.e. The Lancet, 2007).
Dr. Mirijello’s scientific production includes more than 100 publications, including approximately 90 publications in peer-reviewed journals (Impact Factor: 293; H index: 20) such as the Lancet, Alcoholism: Clinical and Experimental Research, Drugs, and CNS Drugs.
His main research interests involve alcohol addiction, the metabolic aspects of alcohol addiction and alcohol liver disease, sepsis, diabetes, hypertension, and venous thromboembolism.
He acts as a reviewer for several scientific peer-reviewed journals (CNS Drugs, Alcoholism Clinical and Experimental Research, Drug and Alcohol Dependence, Alcohol and Alcoholism, Journal of Clinical Medicine, Clinical Cardiology, etc.).