Ameloblastoma, a benign yet aggressive odontogenic tumor known for its recurrence and the severe morbidity from radical surgeries, may benefit from advancements in targeted therapy. We present a case of a 15-year-old girl with ameloblastoma successfully treated with targeted therapy and review the literature with this question: Is anti-MAPK targeted therapy safe and effective for treating ameloblastoma? This systematic review was registered in PROSPERO, adhered to PRISMA guidelines, and searched multiple databases up to December 2023, identifying 13 relevant studies out of 647 records, covering 23 patients treated with MAPK inhibitor therapies. The results were promising as nearly all patients showed a positive treatment response, with four achieving complete radiological remission and others showing substantial reductions in primary, recurrent, and metastatic ameloblastoma sizes. Side effects were mostly mild to moderate. This study presents anti-MAPK therapy as a significant shift from invasive surgical treatments, potentially enhancing life quality and clinical outcomes by offering a less invasive yet effective treatment alternative. This approach could signify a breakthrough in managing this challenging tumor, emphasizing the need for further research into molecular-targeted therapies.

Since the first report from the 1968 Olympic Games, many studies have consistently reported poor oral health in elite athletes without any differences regarding socio-economic status or continental location. Poor oral health is an important issue as it has a clear impact on quality of life, confidence, appearance and socialisation. It also has an impact on sport performance and training with impaired preparation for competition. Many causes to impaired oral health can include nutritional diet and carbohydrate supplementation, oral dehydration, depression of various aspect of the immune function due to intense exercise, negative health behaviours, lack of awareness, time and prioritisation. Facial traumas and oro-dental injuries have to be considered because of their high prevalence among athletes. This update tries to raise awareness of the issues of oral health amongst health-care providers and give simple interventions and strategies for prevention and promotion.

L’obstruction laryngée induite à l’effort (EILO) est une affection caractérisée par le rétrécissement ou la fermeture temporaire du larynx au cours d’un...