With the expanding usage of various devices, which emit static and extremely low-frequency magnetic fields, increases the number of biomedical reports on their influence as well as demand for suitable experimental exposure systems. Experimental setups range from permanent magnets through Helmholtz coils to solenoids; however, almost all of them provide relatively weak magnetic fields of up to 10 mT. Widespread use of devices such as MR scanners imposes intentional as well as unintentional exposure to stronger fields. A typical solenoid produces stronger although less homogeneous field than the most commonly used experimental equipment composed of sets of coaxial coils. In order to provide scalable, relatively strong, low-varying field within experimental volume that is large enough for in vivo as well as in vitro experiments modified solenoids are considered. Variation of the field was reduced by modifying the shape and size of solenoid's cross section. Modified solenoids were modeled analytically, numerically, and as a prototype. Solenoid geometries were optimized for maximal field performance and minimal power consumption. The optimal modified solenoids scalable to desired sizes of the experimental volume and values of maximal magnetic induction intensities are offered. The suggested solenoid modification method can decrease field variation as much as 10.6 times.

Previous studies showed contradictory results of static magnetic field (SMF) influence on behavior, hematological parameters and organ damage. The aim of this study was to investigate influence of subchronic continuous exposure to upward and downward oriented SMF of moderate intensity on behavior, hematological characteristics, heart and kidney tissue of spontaneously hypertensive rats. SH rats exposed to downward oriented SMF demonstrated lack of anxious-like behavior. SMF of either orientation caused decrease in the number of platelets in peripheral blood, granulocytes in the spleen and bone marrow and increase in the number of erythrocytes in the spleen, in both exposed groups. We also demonstrated that spontaneously hypertensive rats exposed to upward oriented SMF exhibited decreased lymphocytes count in blood, decreased bone marrow erythrocytes count and rats exposed to downward oriented SMF had increased lymphocytes count in bone marrow. The results showed adverse effect of differently oriented SMF on hematological parameters of spontaneously hypertensive rats. Also, exposure to different oriented SMF didn't affect their heart and kidney morphological characteristics.