Jan Van Frankenhuyzen

Jan Van Frankenhuyzen

Auto-generated profile, based on publicly available information

Jan Van Frankenhuyzen

Delft University of Technology, Delft, Netherlands

Research Focus & Metrics

Representative Publications

View All Publications
15 October 2026 in World Neurosurgery
Verified
Journal Article
Open access
AIAlessandro Iop
Alessandro Iop
Andrii MatviienkoAndrii Matviienko
Andrii Matviienko
IMIngemar Markström
Ingemar Markström
JFJan Van Frankenhuyzen
Jan Van Frankenhuyzen
JDJohn Van Den Dobbelsteen
John Van Den Dobbelsteen
MRMario Romero
Mario Romero
Simulation-based training is a key component of modern neurosurgical education, providing a repeatable environment for procedural practice. External ventricular drain (EVD) placement is a common emergency procedure performed in the early stages of neurosurgical training. This study presents the design, fabrication, and evaluation of a modular phantom targeting a specific brain subregion, intended to replicate the mechanical and procedural aspects of EVD insertion with improved material efficiency and reusability compared to existing full-brain approaches. A human cranium model was generated from medical imaging data and 3D-printed in two configurations. Both housed a replaceable polyvinyl alcohol (PVA) hydrogel brain sample containing a ventricular cavity. Mechanical tests compared three hydrogel variants for stability and haptic fidelity during controlled catheter advancement. A user study with seven experienced neurosurgeons provided a preliminary qualitative assessment of realism, ergonomics, and simulation fidelity through questionnaires and semi-structured interviews. Modified hydrogel designs with enlarged or reinforced ventricles demonstrated greater mechanical stability and higher insertion resistance (∼0.6 N) compared to the standard configuration (∼0.4 N), with force-displacement profiles suggesting more consistent haptic feedback during ventricular entry. Surgeons rated cranial realism highly (visual M = 4.43, tactile M = 4.00), though brain visual realism scored lower (M = 2.71), likely reflecting the absence of meninges and cortical surface detail. The proposed phantom represents an early-stage platform for EVD simulation, offering reproducibility, low cost, and modularity supporting repeated use and anatomical customization. Further validation with larger and more diverse cohorts is needed to substantiate its educational value.

2 December 2024
Verified
Conference Paper
Open access
JFJan van Frankenhuyzen
Jan van Frankenhuyzen
JDJohn van Den Dobbelsteen
John van Den Dobbelsteen
Andrii MatviienkoAndrii Matviienko
Andrii Matviienko