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Rui Sanches
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Rui Sanches
Center for Neuroscience and Cell Biology, University of Coimbra, Largo Marquês de Pombal, Coimbra, 3004-517, Portugal
Research Focus & Metrics
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Academic Career Length
14Years (2013-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications30 January 2013 in Journal of Neuroinflammation
Journal Article
CGCatarina Gomes
Catarina GomesRFRaquel Ferreira
Raquel FerreiraJGJimmy George
Jimmy GeorgeRSRui Sanches
Rui SanchesDRDiana I Rodrigues
Diana I Rodrigues
Rodrigo Cunha +1
Brain-derived neurotrophic factor (BDNF) has been shown to control microglial responses in neuropathic pain. Since adenosine A2A receptors (A2ARs) control neuroinflammation, as well as the production and function of BDNF, we tested to see if A2AR controls the microglia-dependent secretion of BDNF and the proliferation of microglial cells, a crucial event in neuroinflammation.