Tiehan Cui, Yanxu Mao, Peipei Liu, Congying Liu, Datao You. Findings of the Association for Computational Linguistics: ACL 2025. 2025.

Although large language models (LLMs) have achieved remarkable advancements, their security remains a pressing concern. One major threat is jailbreak attacks, where adversarial prompts bypass model safeguards to generate harmful or objectionable content. Researchers study jailbreak attacks to understand security and robustness of LLMs. However, existing jailbreak attack methods face two main challenges: (1) an excessive number of iterative queries, and (2) poor generalization across models. In addition, recent jailbreak evaluation datasets focus primarily on question-answering scenarios, lacking attention to text generation tasks that require accurate regeneration of toxic content. To tackle these challenges, we propose two contributions: (1) ICE, a novel black-box jailbreak method that employs Intent Concealment and divErsion to effectively circumvent security constraints. ICE achieves high attack success rates (ASR) with a single query, significantly improving efficiency and transferability across different models. (2) BiSceneEval, a comprehensive dataset designed for assessing LLM robustness in question-answering and text-generation tasks. Experimental results demonstrate that ICE outperforms existing jailbreak techniques, revealing critical vulnerabilities in current defense mechanisms. Our findings underscore the necessity of a hybrid security strategy that integrates predefined security mechanisms with real-time semantic decomposition to enhance the security of LLMs.

Agentic chip design combines large language models with electronic design automation (EDA) tools to plan, execute, and revise design operations. Its effectiveness depends on how an agent translates requirements into executable tasks, interprets diagnostic information, and coordinates changes across design stages. This survey examines these relationships across digital design, agent architectures, EDA algorithm and tool development, and evaluation, with additional coverage of analog, mixed-signal, and radio-frequency applications. We compare agentic chip-design methods through the design representations they modify, the feedback used to select revisions, and the procedures used to check correctness and implementation quality. The analysis shows that broader agent control over designs and EDA software expands optimization opportunities while increasing the need to manage dependencies and verify changes across the design flow. We also compare benchmarks and evaluation methods, focusing on functional correctness, implementation quality, and computational cost. These comparisons identify research directions in specification interpretation, failure diagnosis, repository-level integration, cross-stage optimization, and efficient tool use. By synthesizing these findings, this survey aims to guide the research community in developing and evaluating more reliable and efficient chip-design agents.

Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective integration of information from multiple data sources to support accurate retrieval and reasoning. Although large language models (LLMs) perform well in general reasoning tasks, their generated biomedical content often lacks scientific rigor due to the inability to access authoritative biomedical databases and frequently fabricates protein functions, interactions, and structural details that deviate from authentic information. Therefore, we present BioMedSearch, a multi-source biomedical information retrieval framework based on LLMs. The method integrates literature retrieval, protein database and web search access to support accurate and efficient handling of complex biomedical queries. Through sub-queries decomposition, keywords extraction, task graph construction, and multi-source information filtering, BioMedSearch generates high-quality question-answering results. To evaluate the accuracy of question answering, we constructed a multi-level dataset, BioMedMCQs, consisting of 3,000 questions. The dataset covers three levels of reasoning: mechanistic identification, non-adjacent semantic integration, and temporal causal reasoning, and is used to assess the performance of BioMedSearch and other methods on complex QA tasks. Experimental results demonstrate that BioMedSearch consistently improves accuracy over all baseline models across all levels. Specifically, at Level 1, the average accuracy increases from 59.1% to 91.9%; at Level 2, it rises from 47.0% to 81.0%; and at the most challenging Level 3, the average accuracy improves from 36.3% to 73.4%. The code and BioMedMCQs are available at: https://github.com/CyL-ucas/BioMed_Search