Silvia Lomartire

Silvia Lomartire

Auto-generated profile, based on publicly available information

Silvia Lomartire

University of Coimbra, MARE—Marine and Environmental Sciences Centre, Department of Life Sciences, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
15 June 2021 in Marine Drugs
Verified
Journal Article
Open access
PDF file
SLSilvia Lomartire
Silvia Lomartire
JMJoão Carlos Marques
João Carlos Marques
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves
Currently, seaweeds are gaining major attention due to the benefits they give to our health. Recent studies demonstrate the high nutritional value of seaweeds and the powerful properties that seaweeds’ bioactive compounds provide. Species of class Phaeophyceae, phylum Rhodophyta and Chlorophyta possess unique compounds with several properties that are potential allies of our health, which make them valuable compounds to be involved in biotechnological applications. In this review, the health benefits given by consumption of seaweeds as whole food or by assumption of bioactive compounds trough natural drugs are highlighted. The use of seaweeds in agriculture is also highlighted, as they assure soils and crops free from chemicals; thus, it is advantageous for our health. The addition of seaweed extracts in food, nutraceutical, pharmaceutical and industrial companies will enhance the production and consumption/usage of seaweed-based products. Therefore, there is the need to implement the research on seaweeds, with the aim to identify more bioactive compounds, which may assure benefits to human and animal health.

26 April 2021 in Marine Drugs
Verified
Journal Article
Open access
PDF file
SLSilvia Lomartire
Silvia Lomartire
João CotasJoão Cotas
João Cotas
DPDiana Pacheco
Diana Pacheco
JMJoão Carlos Marques
João Carlos Marques
Leonel PereiraLeonel Pereira
Leonel Pereira
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves
Seaweeds are a potential source of bioactive compounds that are useful for biotechnological applications and can be employed in different industrial areas in order to replace synthetic compounds with components of natural origin. Diverse studies demonstrate that there is a solid ground for the exploitation of seaweed bioactive compounds in order to prevent illness and to ensure a better and healthier lifestyle. Among the bioactive algal molecules, phenolic compounds are produced as secondary metabolites with beneficial effects on plants, and also on human beings and animals, due to their inherent bioactive properties, which exert antioxidant, antiviral, and antimicrobial activities. The use of phenolic compounds in pharmaceutical, nutraceutical, cosmetics, and food industries may provide outcomes that could enhance human health. Through the production of healthy foods and natural drugs, bioactive compounds from seaweeds can help with the treatment of human diseases. This review aims to highlight the importance of phenolic compounds from seaweeds, the scope of their production in nature and the impact that these compounds can have on human and animal health through nutraceutical and pharmaceutical products.

Verified
Journal Article
Open access
PDF file
João CotasJoão Cotas
João Cotas
SLSilvia Lomartire
Silvia Lomartire
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves
Leonel PereiraLeonel Pereira
Leonel Pereira
Seaweed, a miscellaneous group of marine algae, has long been recognized for its rich nutritional composition and bioactive compounds, being considered nutraceutical ingredient. This revision delves into the promising role of seaweed-derived nutrients as a beneficial resource for drug discovery and innovative product development. Seaweeds are abundant sources of essential vitamins, minerals, polysaccharides, polyphenols, and unique secondary metabolites, which reveal a wide range of biological activities. These bioactive compounds possess potential therapeutic properties, making them intriguing candidates for drug leads in various medical applications and pharmaceutical drug development. It explores their pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, shedding light on their potential as therapeutic agents. Moreover, the manuscript provides insights into the development of formulation strategies and delivery systems to enhance the bioavailability and stability of seaweed-derived compounds. The manuscript also discusses the challenges and opportunities associated with the integration of seaweed-based nutrients into the pharmaceutical and nutraceutical industries. Regulatory considerations, sustainability, and scalability of sustainable seaweed sourcing and cultivation methods are addressed, emphasizing the need for a holistic approach in harnessing seaweed’s potential. This revision underscores the immense potential of seaweed-derived compounds as a valuable reservoir for drug leads and product development. By bridging the gap between marine biology, pharmacology, and product formulation, this research contributes to the critical advancement of sustainable and innovative solutions in the pharmaceutical and nutraceutical sectors.

31 October 2021 in Processes
Verified
Journal Article
Open access
PDF file
PMPedro Manuel Monteiro
Pedro Manuel Monteiro
SLSilvia Lomartire
Silvia Lomartire
João CotasJoão Cotas
João Cotas
DPDiana Pacheco
Diana Pacheco
JMJoão C. Marques
João C. Marques
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves
Seaweeds are gaining momentum as novel and functional food and feed products. From whole consumption to small bioactive compounds, seaweeds have remarkable flexibility in their applicability, ranging from food production to fertilizers or usages in chemical industries. Regarding food production, there is an increasing interest in the development of novel foods that, at the same time, present high nutritious content and are sustainably developed. Seaweeds, because they require no arable land, no usage of fresh water, and they have high nutritious and bioactive content, can be further explored for the development of newer and functional food products. Fermentation, especially performed by lactic acid bacteria, is a method used to produce functional foods. However, fermentation of seaweed biomass remains an underdeveloped topic that nevertheless demonstrates high potential for the production of new alimentary products that hold and further improve the organoleptic and beneficial properties that these organisms are characterized for. Although further research has to be deployed in this field, the prebiotic and probiotic potential demonstrated by fermented seaweed can boost the development of new functional foods.

9 June 2022 in Marine Drugs
Verified
Journal Article
Open access
PDF file
PMPedro Monteiro
Pedro Monteiro
SLSilvia Lomartire
Silvia Lomartire
João CotasJoão Cotas
João Cotas
JMJoão C. Marques
João C. Marques
Leonel PereiraLeonel Pereira
Leonel Pereira
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves
In recent years, an increased interest in marine macroalgae bioactive compounds has been recorded due to their benefits to human health and welfare. Several of their bioactivities have been demonstrated, such as anti-inflammatory, antioxidant, anticarcinogenic, antibacterial and antiviral behavior. However, there still lacks a clear definition regarding how these compounds exert their bioactive properties. Of all the bioactive compounds derived from marine macroalgae, attention has been focused on phenolic compounds, specifically in phlorotannins, due to their potential for biomedical applications. Phlorotannins are a diverse and wide group of phenolic compounds, with several structural variations based on the monomer phloroglucinol. Among the diverse phlorotannin structures, the eckol-family of phlorotannins demonstrates remarkable bioactivity, notably their anti-tumoral properties. However, the molecular mechanisms by which this activity is achieved remain elusive and sparse. This review focuses on the described molecular mechanisms of anti-tumoral effects by the eckol family of compounds and the future prospects of these molecules for potential application in oncology therapies.
1

1 March 2025
Verified
Book Chapter
Closed access
PDF file
João CotasJoão Cotas
João Cotas
SLSilvia Lomartire
Silvia Lomartire
MMMadalena Mendes
Madalena Mendes
Leonel PereiraLeonel Pereira
Leonel Pereira
Ana Marta GonçalvesAna Marta Gonçalves
Ana Marta Gonçalves