Today’s AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection that requires an early diagnosis with high uncertainty from the clinician. Our aim is to explore the design requirements for AI systems that can support clinical experts in making better decisions for the early diagnosis of sepsis. The study begins with a formative study investigating why clinical experts abandon an existing AI-powered Sepsis predictive module in their electrical health record (EHR) system. We argue that a human-centered AI system needs to support human experts in the intermediate stages of a medical decision-making process (e.g., generating hypotheses or gathering data), instead of focusing only on the final decision. Therefore, we build SepsisLab based on a state-of-the-art AI algorithm and extend it to predict the future projection of sepsis development, visualize the prediction uncertainty, and propose actionable suggestions (i.e., which additional laboratory tests can be collected) to reduce such uncertainty. Through heuristic evaluation with six clinicians using our prototype system, we demonstrate that SepsisLab enables a promising human-AI collaboration paradigm for the future of AI-assisted sepsis diagnosis and other high-stakes medical decision making.

Interactive storytelling is vital for preschooler development. While children's interactive partners have traditionally been their parents and teachers, recent advances in artificial intelligence (AI) have sparked a surge of AI-based storytelling and reading technologies. As these technologies become increasingly ubiquitous in preschoolers' lives, questions arise regarding how they function in practical storytelling and reading scenarios and, how parents, the most critical stakeholders, experience and perceive these technologies. This paper investigates these questions through a qualitative study with 17 parents of children aged 3-6. Our findings suggest that even though AI-based storytelling and reading technologies provide more immersive and engaging interaction, they still cannot meet parents' expectations due to a series of interactive and algorithmic challenges. We elaborate on these challenges and discuss the possible implications of future AI-based interactive storytelling technologies for preschoolers.

Biomedical Question Answering aims to extract an answer to the given question from a biomedical context. Due to the strong professionalism of specific domain, its more difficult to build large-scale datasets for specific domain question answering. Existing methods are limited by the lack of training data, and the performance is not as good as in open-domain settings, especially degrading when facing to the adversarial sample. We try to resolve the above issues. Firstly, effective data augmentation strategies are adopted to improve the model training, including slide window, summarization and round-trip translation. Secondly, we propose a model weighting strategy for the final answer prediction in biomedical domain, which combines the advantage of two models, open-domain model QANet and BioBERT pre-trained in biomedical domain data. Finally, we give adversarial training to reinforce the robustness of the model. The public biomedical dataset collected from PubMed provided by BioASQ challenge is used to evaluate our approach. The results show that the model performance has been improved significantly compared to the single model and other models participated in BioASQ challenge. It can learn richer semantic expression from data augmentation and adversarial samples, which is beneficial to solve more complex question answering problems in biomedical domain.