Lasse Borgholt

Lasse Borgholt

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Lasse Borgholt

Corti, Copenhagen, Denmark

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 July 2023
Verified
Conference Paper
Open access
JEJoakim Edin
Joakim Edin
AJAlexander Junge
Alexander Junge
JHJakob D. Havtorn
Jakob D. Havtorn
LBLasse Borgholt
Lasse Borgholt
MMMaria Maistro
Maria Maistro
LMLars Maaløe
Lars Maaløe
Medical coding is the task of assigning medical codes to clinical free-text documentation. Healthcare professionals manually assign such codes to track patient diagnoses and treatments. Automated medical coding can considerably alleviate this administrative burden. In this paper, we reproduce, compare, and analyze state-of-the-art automated medical coding machine learning models. We show that several models underperform due to weak configurations, poorly sampled train-test splits, and insufficient evaluation. In previous work, the macro F1 score has been calculated sub-optimally, and our correction doubles it. We contribute a revised model comparison using stratified sampling and identical experimental setups, including hyperparameters and decision boundary tuning. We analyze prediction errors to validate and falsify assumptions of previous works. The analysis confirms that all models struggle with rare codes, while long documents only have a negligible impact. Finally, we present the first comprehensive results on the newly released MIMIC-IV dataset using the reproduced models. We release our code, model parameters, and new MIMIC-III and MIMIC-IV training and evaluation pipelines to accommodate fair future comparisons.

19 December 2023 in npj Digital Medicine
Verified
Journal Article
Open access
PDF file
JWJonathan Wenstrup
Jonathan Wenstrup
JHJakob Drachmann Havtorn
Jakob Drachmann Havtorn
LBLasse Borgholt
Lasse Borgholt
SBStig Nikolaj Blomberg
Stig Nikolaj Blomberg
LMLars Maaloe
Lars Maaloe
HCHelle Collatz Christensen
Helle Collatz Christensen
Advanced stroke treatment is time-dependent and, therefore, relies on recognition by call-takers at prehospital telehealth services to ensure fast hospitalisation. This study aims to develop and assess the potential of machine learning in improving prehospital stroke recognition during medical helpline calls. We used calls from 1 January 2015 to 31 December 2020 in Copenhagen to develop a machine learning-based classification pipeline. Calls from 2021 are used for testing. Calls are first transcribed using an automatic speech recognition model and then categorised as stroke or non-stroke using a text classification model. Call-takers achieve a sensitivity of 52.7% (95% confidence interval 49.2–56.4%) with a positive predictive value (PPV) of 17.1% (15.5–18.6%). The machine learning framework performs significantly better (p < 0.0001) with a sensitivity of 63.0% (62.0–64.1%) and a PPV of 24.9% (24.3–25.5%). Thus, a machine learning framework for recognising stroke in prehospital medical helpline calls may become a supportive tool for call-takers, aiding in early and accurate stroke recognition.

28 November 2018 in arXiv
Verified
Preprint
Open access
PDF file
JKJan Kremer
Jan Kremer
LBLasse Borgholt
Lasse Borgholt
LMLars Maaløe
Lars Maaløe
End-to-end automatic speech recognition (ASR) commonly transcribes audio signals into sequences of characters while its performance is evaluated by measuring the word-error rate (WER). This suggests that predicting sequences of words directly may be helpful instead. However, training with word-level supervision can be more difficult due to the sparsity of examples per label class. In this paper we analyze an end-to-end ASR model that combines a word-and-character representation in a multi-task learning (MTL) framework. We show that it improves on the WER and study how the word-level model can benefit from character-level supervision by analyzing the learned inductive preference bias of each model component empirically. We find that by adding character-level supervision, the MTL model interpolates between recognizing more frequent words (preferred by the word-level model) and shorter words (preferred by the character-level model).