Anton Aleksandrovich Denisov

Anton Aleksandrovich Denisov

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Anton Aleksandrovich Denisov

Department of Orthopedic Surgery, University Hospital Mollet, Barcelona, Spain

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 August 2019 in Russian Sklifosovsky Journal "Emergency Medical Care"
Verified
Journal Article
Open access
AYA. V. Yarikov
A. V. Yarikov
AFA. P. Fraerman
A. P. Fraerman
OPO. A. Perlmutter
O. A. Perlmutter
ADA. A. Denisov
A. A. Denisov
SMS. V. Masevnin
S. V. Masevnin
ALA. N. Lavrenyuk
A. N. Lavrenyuk

8 July 2020 in Traumatology and Orthopedics of Russia
Verified
Journal Article
Open access
PDF file
ADA. A. Denisov
A. A. Denisov
DPD. A. Ptashnikov
D. A. Ptashnikov
DMD. A. Mikhaylov
D. A. Mikhaylov
SMS. V. Masevnin
S. V. Masevnin
OSO. A. Smekalenkov
O. A. Smekalenkov
NZN. S. Zaborovskii
N. S. Zaborovskii
Relevance. The development of minimally invasive surgery has led to the development of new methods for surgical treatment of the spine. Conventional surgical technique, such as vertebrotomy is accompanied by a several number of disadvantages (high blood loss, prolonged hospital stay, long intraoperative time, postoperative neurological deficit). An alternative to improve sagittal balance in the spine is to use custom-made hyperlordotic cages, which can also be used for indirect decompression of neural structures. The objective is to compare the degree of segmental and total lumbar lordosis using hyperlordotic cages through ALIF and TLIF with posterior instrumentation.Materials and Methods. A single-center retrospective cohort study using 96 patients treated from 2018 to 2019 about degenerative spinal deformities. Comparison of two groups: group 1 (A) consisted of 30 patients who were held anterior spinal fusion with individual lordotic cages from minimally invasive anterior approach (MISS ALIF) without posterior fixation. Group 2 (B) consisted of 33 patients whom were performed spinal fusion from the posterior approach (TLIF) with Smith-Peterson Osteotomy (SPO) and transpedicular fixation. Measuring segmental and lumbar lordosis, teleradiographs were used in a standing position. For an accurate assessment, the non-commercial available Surgimap software, © Nemaris, was used.Results. Segmental lordosis were superior to preoperative ones. In the intergroup comparison, the ALIF group showed an excellent increase in the enlarged lordosis segment (L3-L4 in 8 degrees; p = 0.0005, L4-L5 in 7 degrees; p = 0.0002, L5-S1 in 7 degrees; p = 0.0001). When conducting an intergroup comparison of total lumbar lordosis in the preoperative period, there was a statistically significant difference between them (p = 0.0043). At the same time, a greater degree of correction of lordosis is shown in ALIF compared to TLIF group (29,1 in comparison with 22,5; p = 0.00005).Conclusion. The results of this study confirm that the using of custom-made lordotic cages can significantly increase segmental and total lumbar lordosis for patients with degenerative scoliosis in adults.

20 December 2017 in Terapevticheskii arkhiv
Verified
Journal Article
Open access
NKN N Kornilov
N N Kornilov
ADA A Denisov
A A Denisov
The prevalence of chronic joint diseases, among which osteoarthritis (OA) prevails, continues to grow worldwide. So far, many OA patients starting to get any kind of treatment only at the stage of organ failure, when the progression of the pathological process cannot be considerably delayed. The long-felt need for a change in thinking how to effectively diagnose and treat OA patients at early stage induced to prepare this review. Its first part is devoted to discussion of the limitations of traditional approaches and to analysis of the current diagnostic capabilities, particularly the clinical features of early OA, its morphological characteristics based on the magnetic resonance imaging and arthroscopic criteria, as well as the perspectives of biochemical and genetic markers implementation.

8 November 2021 in HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
Verified
Journal Article
Closed access
PDF file
ADAnton Denisov
Anton Denisov
NZNikita Zaborovskii
Nikita Zaborovskii
VSVladimir Solovyov
Vladimir Solovyov
MMMikael Mamedov
Mikael Mamedov
DMDmitrii Mikhaylov
Dmitrii Mikhaylov
DPDmitrii Ptashnikov
Dmitrii Ptashnikov
Background: Patients’ expectations are an important determinant in their decision to undergo lumbar spinal surgery—particularly their expectations of recovery after surgery. The Hospital for Special Surgery Lumbar Spine Surgery Expectations Survey (HSS-LSSES) is one tool used to assess this; however, the original version was only available in English. Objective: We sought to evaluate the reliability and validity of a translated and adapted Russian-language version of the HSS-LSSES. Methods: This was a prospective study of 91 patients with degenerative disc disease who underwent lumbar spine surgery with instrumented fixation at a single institution in Saint Petersburg, Russia. Patients were recruited between December 2019 and February 2021 and asked about their expectations of surgery with a translated and adapted Russian version of the HSS-LSSES. To analyze construct validity, participants also completed disease-specific and general quality-of-life scales (Oswestry Disability Index, European Quality of Life–5 Dimensions, and 36-item Short-Form Health Survey). Intraclass correlation coefficients (ICCs; 2-way random effects model, absolute agreement) were used to determine test-retest reliability of the total score of the Russian HSS-LSSES. Internal consistency was evaluated through the estimation of Cronbach’s alpha between the test and retest response of the questionnaire. Results: The test-retest stability of the Russian HSS-LSSES evaluated through the estimation of ICC was found to have good stability. The instrument was shown to have high internal consistency. Conclusion: This study demonstrates that a translated and adapted Russian version of HSS-LSSES had good internal consistency, reliability, construct validity, and no floor and ceiling effects. Therefore, we recommend its use as a tool for evaluating Russian-speaking patients’ expectations before lumbar spine surgery.

3 October 2023 in Russian Journal of Spine Surgery (Khirurgiya Pozvonochnika)
Verified
Journal Article
Open access
PDF file
NZNikita Sergeevich Zaborovskii
Nikita Sergeevich Zaborovskii
ADAnton Aleksandrovich Denisov
Anton Aleksandrovich Denisov
DMDmitrii Arkadyevich Mikhaylov
Dmitrii Arkadyevich Mikhaylov
OSOleg Anatolyevich Smekalenkov
Oleg Anatolyevich Smekalenkov
SMSergey Vladimirovich Masevnin
Sergey Vladimirovich Masevnin
ЮПЮрий Юрьевич Поляков
Юрий Юрьевич Поляков
Objective. To determine the main demographic factors that influence preoperative expectations of patients with degenerative diseases of the lumbosacral spine.Material and Methods. A cross-sectional study was performed for 103 patients with degenerative diseases of the lumbosacral spine who were scheduled for surgery in the period from 2019 to 2021. General demographic data, level of patient’s education and the presence of previous surgeries were taken into account. Expectations for surgical treatment outcome were assessed using a translated and adapted Russian version of the Hospital for Special Surgery – Lumbar Spine Surgery Expectations Survey (HSS-LSSES) questionnaire. The quality of life of patients was assessed using the general questionnaires: European Quality of Life-5 Dimensions (EQ-5D-5L) and the 36-item Short-Form Health Survey (SF-36), as well as the disease-specific Oswestry Disability Index (ODI).Results. It was found that, according to HSS-LSSES, patients’ expectations for the upcoming surgical intervention are the higher, the older the patient’s age, the higher the general and emotional state of health, vitality, ODI scores, as well as the severity of pain syndrome, and the lower the mental health score. Patients with a high level of education and prior spinal surgery have lower expectations for subsequent surgery.Conclusion. The expectations of patients for the surgical treatment for degenerative disease of the lumbosacral spine depend on the patient’s age, level of education, anamnesis and severity of decline in the quality of life.

31 December 2020 in Orthopedic Reviews
Verified
Journal Article
Open access
PDF file
ADAnton Denisov
Anton Denisov
NZNikita S. Zaborovsky
Nikita S. Zaborovsky
DPDmitry A. Ptashnikov
Dmitry A. Ptashnikov
DMDmitry A. Mikhailov
Dmitry A. Mikhailov
SMSergey V. Masevnin
Sergey V. Masevnin
OSOleg A. Smekalenkov
Oleg A. Smekalenkov
This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale.