Antiviral drugs are a class of medicines particularly used for the treatment of viral infections. Drugs that combat viral infections are called antiviral drugs. Viruses are among the major pathogenic agents that cause number of serious diseases in humans, animals and plants. Viruses cause many diseases in humans, from self resolving diseases to acute fatal diseases. Developing strategies for the antiviral drugs are focused on two different approaches: Targeting the viruses themselves or the host cell factors. Antiviral drugs that directly target the viruses include the inhibitors of virus attachment, inhibitors of virus entry, uncoating inhibitors, polymerase inhibitors, protease inhibitors, inhibitors of nucleoside and nucleotide reverse transcriptase and the inhibitors of integrase. The inhibitors of protease (ritonavir, atazanavir and darunavir), viral DNA polymerase (acyclovir, tenofovir, valganciclovir and valacyclovir) and of integrase (raltegravir) are listed among the Top 200 Drugs by sales during 2010s. Still no effective antiviral drugs are available for many viral infections. Though, there are a couple of drugs for herpesviruses, many for influenza and some new antiviral drugs for treating hepatitis C infection and HIV. Action mechanism of antiviral drugs consists of its transformation to triphosphate following the viral DNA synthesis inhibition. An analysis of the action mechanism of known antiviral drugs concluded that they can increase the cell’s resistance to a virus (interferons), suppress the virus adsorption in the cell or its diffusion into the cell and its deproteinisation process in the cell (amantadine) along with antimetabolites that causes the inhibition of nucleic acids synthesis. This review will address currently used antiviral drugs, mechanism of action and antiviral agents reported against COVID-19.

The advent of antibiotics revolutionized medical care resulting in significantly reduced mortality and morbidity caused by infectious diseases. However, excessive use of antibiotics has led to the development of antibiotic resistance and indeed, the incidence of multidrug‐resistant pathogens is considered as a major disadvantage in medication strategy, which has led the scholar's attention towards innovative antibiotic sources in recent years. Medicinal plants contain a variety of secondary metabolites with a wide range of therapeutic potential against the resistant microbes. Therefore, the aim of this review is to explore the antibacterial potential of traditional herbal medicine against bacterial infections. More than 200 published research articles reporting the therapeutic potential of medicinal plants against drug‐resistant microbial infections were searched using different databases such as Google Scholar, Science Direct, PubMed and the Directory of Open Access Journals (DOAJ), etc., with various keywords like medicinal plants having antibacterial activities, antimicrobial potentials, phytotherapy of bacterial infection, etc. Articles were selected related to the efficacious herbs easily available to local populations addressing common pathogens. Various plants such as Artocarpus communis, Rheum emodi, Gentiana lutea L., Cassia fistula L., Rosemarinus officinalis, Argemone maxicana L, Hydrastis canadensis, Citrus aurantifolia, Cymbopogon citrates, Carica papaya, Euphorbia hirta, etc, were found to have significant antibacterial activities. Although herbal preparations have promising potential in the treatment of multidrug‐resistant bacterial infection, still more research is required to isolate phytoconstituents, their mechanism of action as well as to find their impacts on the human body.

Background: Dengue fever is a vector-borne infectious tropical disease caused by the dengue virus, the most common arthropod-borne infection in humans. According to WHO, the best strategy to avoid dengue endemic is to educate people about the disease and preventative measures? Despite the efforts to avoid the dengue virus, the newest national survey statistics show that dengue fever is still on the increase among the population. The major goal of this study was to examine university students' knowledge of dengue and preventative measures, as well as to determine the relationship between awareness of dengue and drivers of knowledge of dengue infection in Government College University Faisalabad students. Aim: The aim of this review is to highlight Dengue fever (break-borne fever). Materials and methods: This was a survey review article. This research work was conducted at Government College University, Faisalabad. And this research work was conducted in three months (Between February 2020 and April 2020). A cross-sectional study investigation was carried out. A total of 500 students were interviewed, with pre-tested questioners being used. Results: A cross-sectional investigation was carried out. A total of 500 students were interviewed, with pre-tested questioners being used. The sampling was done in a convenient manner. In Government College University Faisalabad, several medical terminologies were put in plain English, and interviewers were trained for data collecting. The research was carried out at Government College University in Faisalabad. The course of study was also thought to have an influence on Dengue fever knowledge. SPSS was used to examine the findings of this investigation. The total score range was 25. The participants (26.4%) showed scores from a range of 10 or below 10 which means they had poor knowledge about dengue awareness. While the participants (45.4%) showed scores from a range of 11 to 18 which means they had fair knowledge about dengue awareness. The participants (28.2%) s showed scores ranging from 19 to 25 which means they had good knowledge about dengue fever awareness. Conclusion: Of this study is that knowledge is poor between the study respondents while the majority of persons had clear understanding of fever, headache, joint pain as general signs and symptoms of dengue viral fever. However, a huge proportion exhibited vague opinions of other different signs and symptoms involving muscular pain and skin rashes. Only rare of them knew that dengue viral fever is caused by mosquito bites, and was conscious that the mosquito causing dengue breeds in artificially collected water.

Skin is a very sensitive organ of the body. Skin infections occur due to its exposure to environmental changes, and interaction with different substances like allergens, chemicals, and microbes. Atopic dermatitis is an inflammatory skin problem usually caused by genetic and environmental factors. Food allergy is considered to be the cause of eczema in children. Symptoms include redness, blisters on skin, itching, and scaly bumpy skin mostly appears on neck, legs, hands and arms. Different lotions, creams, moisturizers are used to cure eczema. In traditional medicine, some medicinal plants are used worldwide to cure skin infections with no side effects. They also have the potential to cure eczema. Homogenized Aloe vera gel is used to cure atopic eczema. Aloe Vera gel contains polysaccharides, enzymes, minerals and vitamins. This study was carried out with the aim to evaluate the efficiency of Aloe vera to cure inflammatory skin induced by DNCB (2, 4‐Dinitrochlorobenzene) in rats. This study defined a dose to cure Atopic dermatitis (Eczema) and for comparative dose analysis of Aloe vera to cure Atopic dermatitis at different doses.. The results of present study depicted that Aloe Vera gel extract have significant anti‐inflammatory property particularly in increased dose of gel extract