Background: The aim of this report is to describe ocular side effects in patients who received one of the two COVID-19 vaccines – Astra Zeneca or Pfizer-Biontech and to contribute to the common understanding of the COVID-19 vaccination process. Results: Three patients reactivated underlying herpetic disease and developed uveitis and keratitis. Two of them were vaccinated with Pfizer and one was with Astra Zeneca. Two patients were vaccinated with Pfizer-Biontech and had thrombosis on the 8th and 10th days following the day of vaccination. The man has diagnosed with nonarteritic anterior ischemic optic neuropathy and the woman had a subarachnoid haemorrhage, ptosis of upper eyelid and deviated eyeball. Conclusion: There is a causal relationship between vaccines and the underlying disease. For more details, further large studies are necessary.
Introduction: The eyelids are a common site for skin tumours and account for 5–10% of all skin tumours. Treatment is mainly surgical and aims to preserve the anatomical structure of the eyelid, its function and not least its aesthetic appearance. Aim: Presentation of recurrence and complication rates of tumour-related eyelid surgery in a cohort of 450 tumours. Results: Analysis of a cohort of 450 tumours operated on revealed 13 (2.8%) operations with recurrences and 32 (7%) with complications. The statistical significance of recurrences was observed for the involved and uninvolved ciliary margin. At the temporal canthus, 23.1% of recurrences occurred compared to 7.7% at the medial canthus. SGC has the highest recurrence rate. Complications include the following: ectropion, dehiscence, gross cicatrix with normal function, retraction, post-radiation damage, sub-graft haemorrhage and graft rejection. Conclusions: The recurrence rate of eyelid tumours is lower than that of complications. The choice of surgical technique determines the frequency of complications and histological control of the excised tissue, as well as the frequency of recurrences.
Facial skin defect reconstruction in medial-canthal area of the lids can be a challenge even when performed by a skilled surgeon. The excision of large tumors in this area leads to significant surgical defects that cannot be repaired by merely closing the wound. The glabellar area provides a source of redundant skin with similar characteristics to that of the medial-canthal lid area. The purpose show the possibility of the glabellar flap technique surgery in patients after tumor excision in the medial canthal area with the formation of a large surgical defect and especially those with defect under the medial canthal tendon. We selected 15 well-documented retrospective cases of patients operated over 2 years and followed up for a minimum of 36 months, who underwent surgery with a glabellar flap technique. Patients were operated with V-Y glabellar rotation, advancement, or combined transposition flap techniques. According to the defect’s location, we divided the patients into three groups: upper, medial, and lower surgical defects. A satisfactory functional result was obtained in all the patients. In most of them, the cosmetic results were also good. No additional surgical procedures were required in any of the patients. Our experience showed excellent results with the glabellar flap technique in all three types of lesions in the medial canthal zone—upper, medial, and especially lower which until recently was thought to be inappropriate.
20 February 2023 in Biotechnology & Biotechnological Equipment
Eyelids are a small anatomical structure, yet they contain several histological layers from which benign and malignant tumours can originate. Compared to other parts of the face, the eyelids are often the first place where neoplasms or disease changes are noticed. The aim of this study was to analyze eyelid tumours over a 10-year period. A retrospective study of 436 patients (450 eyes) who underwent oculoplastic surgery in an ophthalmology department over a 10-year period was performed. Descriptive, dispersion and correlation analyses were performed. The demographic analysis provided a clear assessment of the distribution and incidence of eyelid tumours according to age, size, histology and place of residence. Age and malignancy were in a positively significant relationship and increased together. The cases of benign eyelid tumours began to increase in terms of number out of the total cases observed after the age of 40, and malignant tumours after the age of 60. The trend in benign tumours continued until the age of 70, when the increase became four-fold, after which they decreased again at the expense of malignant tumours, which were already increased six-fold by the age of 70. Eighty percent of all malignant tumours of the eyelids were diagnosed after 60 years of age. A patient with an eyelid tumour is to be referred for treatment to an ophthalmologist by medical specialists of all specialties. Early patient referral is directly related to treatment success.
Background: Optical coherence tomography (OCT) is a modern, non-invasive technique for examining the posterior segment of the eye in vivo. The quality of images is crucial for the diagnostic process. Despite good image quality and high signal strength, we still obtain images with less relevant diagnostic data, especially in relation to RNFL and GCL thickness in myopic and hyperopic eyes. Aim: To evaluate the change of RNFL, GCL thickness and rim and disk areas in myopic eyes that underwent OCT examination before and after refractive correction with contact lenses or glasses. Method: A prospective cross-sectional pilot study included 43 eyes in 22 patients with myopia and hyperopia, with or without astigmatism. Patients were examined using OCT with and without contact lenses or glasses. Results: RNFL thickness, GCL thickness, rim area and disk area average and minimum values were significantly changed after correction with glasses or contact lenses. Conclusion: Myopic patients with greater than −2.50 D have to be examined using OCT with their contact lens or glasses corrections in the case of borderline data. Uncorrected myopic eyes show a thinner RNFL and GCL and smaller disk areas, which may mislead ophthalmologists.