Dr. Che-Chia Hsu obtained the Ph.D. degree from National Cheng Kung University in Taiwan and completed his postdoctoral training at Department of Cancer Biology of Wake Forest University School of Medicine. He is well-trained in the field of cancer biology and equipped with strong expertise in biochemical and molecular biology techniques and genetically engineered mouse modeling during his Ph.D. and postdoctoral training. Currently, he is an Assistant Professor at Department of Pathology of Duke University School of Medicine. His research focuses on dissecting mitochondrial functions in cancer metabolism, understanding mitochondrial dynamics in cellular functions and human diseases and identifying potential metabolic vulnerabilities of cancer initiation, progression and metastasis using several in vitro, ex vivo and in vivo genetical approaches such as CRISPR/Cas9 knockout, mouse/ human organoid cultures and genetically engineered mouse models. Lavaraging biochemical and genetical techniques and tools enable to characterize detailed molecular mechanisms regulated by metabolic pathways and developing potential metabolic interventions for targeting cancers. Dr. Che-Chia Hsu’s team has been identified inositol metabolism plays important roles in modulating mitochondrial functions and prostate cancer progression. Imbalance of inositol metabolism can cause aberrant mitochondrial dynamics leading to several diseases such as metabolic diseases, neurodegenerative diseases and cancers