Background: This study aimed to develop an algorithm for multilabel classification according to the distance from carina to endotracheal tube (ETT) tip (absence, shallow > 70 mm, 30 mm ≤ proper ≤ 70 mm, and deep position < 30 mm) with the application of automatic segmentation of the trachea and the ETT on chest radiographs using deep convolutional neural network (CNN). Methods: This study was a retrospective study using plain chest radiographs. We segmented the trachea and the ETT on images and labeled the classification of the ETT position. We proposed models for the classification of the ETT position using EfficientNet B0 with the application of automatic segmentation using Mask R-CNN and ResNet50. Primary outcomes were favorable performance for automatic segmentation and four-label classification through five-fold validation with segmented images and a test with non-segmented images. Results: Of 1985 images, 596 images were manually segmented and consisted of 298 absence, 97 shallow, 100 proper, and 101 deep images according to the ETT position. In five-fold validations with segmented images, Dice coefficients [mean (SD)] between segmented and predicted masks were 0.841 (0.063) for the trachea and 0.893 (0.078) for the ETT, and the accuracy for four-label classification was 0.945 (0.017). In the test for classification with 1389 non-segmented images, overall values were 0.922 for accuracy, 0.843 for precision, 0.843 for sensitivity, 0.922 for specificity, and 0.843 for F1-score. Conclusions: Automatic segmentation of the ETT and trachea images and classification of the ETT position using deep CNN with plain chest radiographs could achieve good performance and improve the physician’s performance in deciding the appropriateness of ETT depth.

Removing noise from images, a.k.a image denoising, can be a very challenging task since the type and amount of noise can greatly vary for each image due to many factors including a camera model and capturing environments. While there have been striking improvements in image denoising with the emergence of advanced deep learning architectures and real-world datasets, recent denoising networks struggle to maintain performance on images with noise that has not been seen during training. One typical approach to address the challenge would be to adapt a denoising network to new noise distribution. Instead, in this work, we shift our focus to adapting the input noise itself, rather than adapting a network. Thus, we keep a pretrained network frozen, and adapt an input noise to capture the fine-grained deviations. As such, we propose a new denoising algorithm, dubbed Learning-to-Adapt-Noise (LAN), where a learnable noise offset is directly added to a given noisy image to bring a given input noise closer towards the noise distribution a denoising network is trained to handle. Consequently, the proposed framework exhibits performance improvement on images with unseen noise, displaying the potential of the proposed research direction. The code is available at https://github.com/chjinny/LAN