Christos Mademlis, MD, MSc, PhD(c) is an Internal Medicine resident at Hippokration General Hospital, Thessaloniki, Greece, currently pursuing training in Gastroenterology. He earned his medical degree from Aristotle University of Thessaloniki and completed postgraduate studies in Research Methodology in Medicine and Health Sciences. His academic and research interests include gastroenterology, hepatology, cardiometabolic medicine, and clinical epidemiology, with a strong focus on systematic reviews, meta-analyses, and evidence synthesis. His work has examined the efficacy of biologic agents and small molecules in UC, the therapeutic role of semaglutide in MASH, and key methodological aspects of clinical research. In parallel with his research activities, he is actively engaged in clinical practice across internal medicine, emergency medicine, and gastroenterology.