Dr. Fraser is a Fellow of the Royal College of Physicians and Surgeons of Canada and was awarded a Canadian Institutes of Health Research (CIHR) Strategic Training Fellowship in the Canadian Child Health Clinician Scientist Program. Dr. Fraser's research includes epidemiological studies, identification of prognostic disease biomarkers and investigation of cellular mechanisms. Dr. Fraser’s research involves several mouse models of brain injury, collection of biological samples from children with acquired brain injury for laboratory analyses (blood and cerebrospinal fluid) and clinical studies on brain injury pathophysiology and epidemiology. More specifically, he is focused on determining the cellular mechanisms underlying acquired brain injury in trauma, diabetic ketoacidosis and severe sepsis. His current thrust is to determine if/how systemic inflammation causes breakdown of the blood-brain barrier and subsequent brain dysfunction. This work includes mouse disease models complemented with the use of human tissues for well-controlled in vitro laboratory studies. In parallel, clinical and biomarker experiments are determining the sensitivity and specificity for prognosticating severity of acquired brain injuries. Dr. Fraser is Director of the Translational Research Centre and he is Chair of the Department of Paediatrics Financial Management Committee.