My research centers on the immunosuppressive mechanisms within the tumor microenvironment and their impact on the efficacy of immunotherapies. I am particularly interested in how endothelial cell metabolism and plasticity contribute to vascular remodeling, immune evasion, and resistance to CAR-T cell therapy. By integrating tumor immunology, vascular biology, and metabolic regulation, I aim to develop innovative therapeutic strategies and next-generation immunotherapies for solid tumors.