The number of microbiome-related studies has notably increased the availability of data on human microbiome composition and function. These studies provide the essential material to deeply explore host-microbiome associations and their relation to the development and progression of various complex diseases. Improved data-analytical tools are needed to exploit all information from these biological datasets, taking into account the peculiarities of microbiome data, i.e., compositional, heterogeneous and sparse nature of these datasets. The possibility of predicting host-phenotypes based on taxonomy-informed feature selection to establish an association between microbiome and predict disease states is beneficial for personalized medicine. In this regard, machine learning (ML) provides new insights into the development of models that can be used to predict outputs, such as classification and prediction in microbiology, infer host phenotypes to predict diseases and use microbial communities to stratify patients by their characterization of state-specific microbial signatures. Here we review the state-of-the-art ML methods and respective software applied in human microbiome studies, performed as part of the COST Action ML4Microbiome activities. This scoping review focuses on the application of ML in microbiome studies related to association and clinical use for diagnostics, prognostics, and therapeutics. Although the data presented here is more related to the bacterial community, many algorithms could be applied in general, regardless of the feature type. This literature and software review covering this broad topic is aligned with the scoping review methodology. The manual identification of data sources has been complemented with: (1) automated publication search through digital libraries of the three major publishers using natural language processing (NLP) Toolkit, and (2) an automated identification of relevant software repositories on GitHub and ranking of the related research papers relying on learning to rank approach.

Background: Wearable sensing and information and communication technologies are key enablers driving the transformation of health care delivery toward a new model of connected health (CH) care. The advances in wearable technologies in the last decade are evidenced in a plethora of original articles, patent documentation, and focused systematic reviews. Although technological innovations continuously respond to emerging challenges and technology availability further supports the evolution of CH solutions, the widespread adoption of wearables remains hindered. Objective: This study aimed to scope the scientific literature in the field of pervasive wearable health monitoring in the time interval from January 2010 to February 2019 with respect to four important pillars: technology, safety and security, prescriptive insight, and user-related concerns. The purpose of this study was multifold: identification of (1) trends and milestones that have driven research in wearable technology in the last decade, (2) concerns and barriers from technology and user perspective, and (3) trends in the research literature addressing these issues. Methods: This study followed the scoping review methodology to identify and process the available literature. As the scope surpasses the possibilities of manual search, we relied on the natural language processing tool kit to ensure an efficient and exhaustive search of the literature corpus in three large digital libraries: Institute of Electrical and Electronics Engineers, PubMed, and Springer. The search was based on the keywords and properties to be found in articles using the search engines of the digital libraries. Results: The annual number of publications in all segments of research on wearable technology shows an increasing trend from 2010 to February 2019. The technology-related topics dominated in the number of contributions, followed by research on information delivery, safety, and security, whereas user-related concerns were the topic least addressed. The literature corpus evidences milestones in sensor technology (miniaturization and placement), communication architectures and fifth generation (5G) cellular network technology, data analytics, and evolution of cloud and edge computing architectures. The research lag in battery technology makes energy efficiency a relevant consideration in the design of both sensors and network architectures with computational offloading. The most addressed user-related concerns were (technology) acceptance and privacy, whereas research gaps indicate that more efforts should be invested into formalizing clear use cases with timely and valuable feedback and prescriptive recommendations. Conclusions: This study confirms that applications of wearable technology in the CH domain are becoming mature and established as a scientific domain. The current research should bring progress to sustainable delivery of valuable recommendations, enforcement of privacy by design, energy-efficient pervasive sensing, seamless monitoring, and low-latency 5G communications. To complement technology achievements, future work involving all stakeholders providing research evidence on improved care pathways and cost-effectiveness of the CH model is needed.

The Internet of things (IoT) has emerged as a topic of intense interest among the research and industrial community as it has had a revolutionary impact on human life. The rapid growth of IoT technology has revolutionized human life by inaugurating the concept of smart devices, smart healthcare, smart industry, smart city, smart grid, among others. IoT devices’ security has become a serious concern nowadays, especially for the healthcare domain, where recent attacks exposed damaging IoT security vulnerabilities. Traditional network security solutions are well established. However, due to the resource constraint property of IoT devices and the distinct behavior of IoT protocols, the existing security mechanisms cannot be deployed directly for securing the IoT devices and network from the cyber-attacks. To enhance the level of security for IoT, researchers need IoT-specific tools, methods, and datasets. To address the mentioned problem, we provide a framework for developing IoT context-aware security solutions to detect malicious traffic in IoT use cases. The proposed framework consists of a newly created, open-source IoT data generator tool named IoT-Flock. The IoT-Flock tool allows researchers to develop an IoT use-case comprised of both normal and malicious IoT devices and generate traffic. Additionally, the proposed framework provides an open-source utility for converting the captured traffic generated by IoT-Flock into an IoT dataset. Using the proposed framework in this research, we first generated an IoT healthcare dataset which comprises both normal and IoT attack traffic. Afterwards, we applied different machine learning techniques to the generated dataset to detect the cyber-attacks and protect the healthcare system from cyber-attacks. The proposed framework will help in developing the context-aware IoT security solutions, especially for a sensitive use case like IoT healthcare environment.

Ambient-assisted living (AAL) is promising to become a supplement of the current care models, providing enhanced living experience to people within context-aware homes and smart environments. Activity recognition based on sensory data in AAL systems is an important task because 1) it can be used for estimation of levels of physical activity, 2) it can lead to detecting changes of daily patterns that may indicate an emerging medical condition, or 3) it can be used for detection of accidents and emergencies. To be accepted, AAL systems must be affordable while providing reliable performance. These two factors hugely depend on optimizing the number of utilized sensors and extracting robust features from them. This paper proposes a generic feature engineering method for selecting robust features from a variety of sensors, which can be used for generating reliable classification models. From the originally recorded time series and some newly generated time series [i.e., magnitudes, first derivatives, delta series, and fast Fourier transformation (FFT)-based series], a variety of time and frequency domain features are extracted. Then, using two-phase feature selection, the number of generated features is greatly reduced. Finally, different classification models are trained and evaluated on an independent test set. The proposed method was evaluated on five publicly available data sets, and on all of them, it yielded better accuracy than when using hand-tailored features. The benefits of the proposed systematic feature engineering method are quickly discovering good feature sets for any given task than manually finding ones suitable for a particular task, selecting a small feature set that outperforms manually determined features in both execution time and accuracy, and identification of relevant sensor types and body locations automatically. Ultimately, the proposed method could reduce the cost of AAL systems by facilitating execution of algorithms on devices with limited resources and by using as few sensors as possible.

Air pollution is becoming a rising and serious environmental problem, especially in urban areas affected by an increasing migration rate. The large availability of sensor data enables the adoption of analytical tools to provide decision support capabilities. Employing sensors facilitates air pollution monitoring, but the lack of predictive capability limits such systems’ potential in practical scenarios. On the other hand, forecasting methods offer the opportunity to predict the future pollution in specific areas, potentially suggesting useful preventive measures. To date, many works tackled the problem of air pollution forecasting, most of which are based on sequence models. These models are trained with raw pollution data and are subsequently utilized to make predictions. This paper proposes a novel approach evaluating four different architectures that utilize camera images to estimate the air pollution in those areas. These images are further enhanced with weather data to boost the classification accuracy. The proposed approach exploits generative adversarial networks combined with data augmentation techniques to mitigate the class imbalance problem. The experiments show that the proposed method achieves robust accuracy of up to 0.88, which is comparable to sequence models and conventional models that utilize air pollution data. This is a remarkable result considering that the historic air pollution data is directly related to the output—future air pollution data, whereas the proposed architecture uses camera images to recognize the air pollution—which is an inherently much more difficult problem.

Scene classification relying on images is essential in many systems and applications related to remote sensing. The scientific interest in scene classification from remotely collected images is increasing, and many datasets and algorithms are being developed. The introduction of convolutional neural networks (CNN) and other deep learning techniques contributed to vast improvements in the accuracy of image scene classification in such systems. To classify the scene from areal images, we used a two-stream deep architecture. We performed the first part of the classification, the feature extraction, using pre-trained CNN that extracts deep features of aerial images from different network layers: the average pooling layer or some of the previous convolutional layers. Next, we applied feature concatenation on extracted features from various neural networks, after dimensionality reduction was performed on enormous feature vectors. We experimented extensively with different CNN architectures, to get optimal results. Finally, we used the Support Vector Machine (SVM) for the classification of the concatenated features. The competitiveness of the examined technique was evaluated on two real-world datasets: UC Merced and WHU-RS. The obtained classification accuracies demonstrate that the considered method has competitive results compared to other cutting-edge techniques.