Fiona Ye Rojo Acero

Ms. Fiona Ye Rojo Acero

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Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 August 2026 in Polymers
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Journal Article
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Fiona Ye Rojo AceroFiona Ye Rojo Acero
Fiona Ye Rojo Acero
DHDaniel Felipe de Castro Hernández
Daniel Felipe de Castro Hernández
MARIA LISSETH FLORES CEDILLOMARIA LISSETH FLORES CEDILLO
MARIA LISSETH FLORES CEDILLO
JUJuan José Uriarte
Juan José Uriarte
AHAinhoa Herrero
Ainhoa Herrero
LRLuis Rodriguez-Lorenzo
Luis Rodriguez-Lorenzo
Extrusion-based bioprinting imposes stringent mechanical constraints on bioink formulations, yet the rheological parameters governing cell survival during the printing process are rarely reported in a standardized way, limiting cross-study comparison. In this work, we systematically characterized the viscoelastic properties of alginate/methylcellulose bioinks incorporating strontium-enriched hydroxyapatite (Sr-OHAp) particles and Poloxamer 188, and assessed their effect on PANC-1 cell viability in bioprinted constructs. The power law consistency index K and pseudoplasticity index n were used as quantitative descriptors of bioink behavior. Addition of Poloxamer 188 reduced K by 52.1% in particle-free inks and by 64.6% in particle-containing inks, while n remained largely unchanged (≤2% variation), indicating that particles selectively modulate consistency without compromising shear-thinning behavior. On day 1, bioprinted constructs showed lower cell viability than cell-seeded scaffolds (53.9–58.9% vs. 96.7%); however, constructs containing Sr-OHAp (B3) displayed progressive recovery, reaching 84.0% viability by day 7, compared to 72.9% for particle-free bioinks (B1). These results demonstrate that Sr-OHAp particles act as rheological sensitizers that reduce extrusion-induced shear stress while simultaneously promoting long-term cell recovery, likely through their bioactive surface chemistry. We propose that systematic reporting of K and n indices should become standard practice in bioprinting studies to enable rational bioink design and consistent knowledge accumulation across the field.