Gino De Angelis

Dr. Gino De Angelis

Canadian Agency for Drugs and Technologies in Health, Ottawa, Ontario, Canada
orcid

Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
10 January 2014 in PLOS ONE
Verified
Journal Article
Open access
PDF file
LBLucie Brosseau
Lucie Brosseau
PRPrinon Rahman
Prinon Rahman
KTKarine Toupin-April
Karine Toupin-April
SPStéphane Poitras
Stéphane Poitras
JKJudy King
Judy King
JMJessica McEwan
Jessica McEwan
Clinical practice CPGs (CPGs) have been developed to summarize evidence related to the management of osteoarthritis (OA). CPGs facilitate uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of the present review were: 1) to assess the quality of the CPGs on non-pharmacological management of OA; using a standardized and validated instrument - the Appraisal of Guidelines Research and Evaluation (AGREE II) tool - by three pairs of trained appraisers; and 2) to summarize the recommendations based on only high-quality existing CPGs. Scientific literature databases from 2001 to 2013 were systematically searched for the state of evidence, with 17 CPGs for OA being identified. Most CPGs effectively addressed only a minority of AGREE II domains. Scope and purpose was effectively addressed in 10 CPGs on the management of OA, stakeholder involvement in 12 CPGs, rigour of development in 10 CPGs, clarity/presentation in 17 CPGs, editorial independence in 2 CPGs, and applicability in none of the OA CPGs. The overall quality of the included CPGs, according to the 7-point AGREE II scoring system, is 4.8±0.41 for OA. Therapeutic exercises, patient education, transcutaneous electrical nerve stimulation, acupuncture, orthoses and insoles, heat and cryotherapy, patellar tapping, and weight control are commonly recommended for the non-pharmacological management of OA by the high-quality CPGs. The general clinical management recommendations tended to be similar among high-quality CPGs, although interventions addressed varied. Non-pharmacological management interventions were superficially addressed in more than half of the selected CPGs. For CPGs to be standardized uniform creators should use the AGREE II criteria when developing CPGs. Innovative and effective methods of CPG implementation to users are needed to ultimately enhance the quality of life of arthritic individuals.

1 July 2012 in Archives of Physical Medicine and Rehabilitation
Verified
Journal Article
Closed access
LLLaurianne Loew
Laurianne Loew
LBLucie Brosseau
Lucie Brosseau
GWGeorge A Wells
George A Wells
PTPeter Tugwell
Peter Tugwell
GKGlen P Kenny
Glen P Kenny
OPOttawa Panel
Ottawa Panel

1 June 2011 in Physical Therapy
Verified
Journal Article
Open access
PDF file
LBLucie Brosseau
Lucie Brosseau
GWGeorge A. Wells
George A. Wells
PTPeter Tugwell
Peter Tugwell
MEMary Egan
Mary Egan
CDClaire-Jehanne Dubouloz
Claire-Jehanne Dubouloz
ATAdam Teav
Adam Teav
Background and Purpose. The objective of this review was to construct an updated evidence-based clinical practice guideline on the use of physical activity and

19 May 2014 in PLOS ONE
Verified
Journal Article
Open access
PDF file
LBLucie Brosseau
Lucie Brosseau
PRPrinon Rahman
Prinon Rahman
SPStéphane Poitras
Stéphane Poitras
KTKarine Toupin-April
Karine Toupin-April
GPGail Paterson
Gail Paterson
JEJessica Mc Ewan
Jessica Mc Ewan
Clinical practice guidelines (CPGs) have been developed to summarize evidence about the management of rheumatoid arthritis (RA) and facilitate the uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of this review was to assess the quality of CPGS on non-pharmacological management of RA with a standardized and validated instrument - the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool and summarize the key recommendations from these CPGs. Scientific literature databases from 2001 to 2013 were systematically searched and a total of 13 CPGs for RA was identified. Only a minority of AGREE II domains were effectively addressed by the CPGS. Scope and purpose was effectively addressed in 10 out of 13 CPGs, stakeholder involvement in 11 CPGs, rigor of development in 6 CPGs, clarity/presentation in 9 CPGs, editorial independence in 1 CPGs, and applicability in none of the CPGs. The overall quality of the included CPGs according to the 7-point AGREE II scoring system was 4.8±1.04. Patient education/self-management, aerobic, dynamic and stretching exercises were the commonly recommended for the non-pharmacological management of RA by the high-quality CPGs. The general clinical management recommendations tended to be similar among high-quality CPGs. Non-pharmacological management interventions were superficially addressed in more than half of the selected CPGs. CPGs creators should use the AGREE II criteria when developing guidelines. Innovative and effective methods of CPGs implementation to users are needed to ultimately enhance the quality of life of arthritic individuals. In addition, it was difficult to establish between strongly recommended, recommended and weakly recommended, as there is no consensus between the strength of the recommendations between the appraised CPGs.

1 October 2012 in Journal of Bodywork and Movement Therapies
Verified
Journal Article
Closed access
LBLucie Brosseau
Lucie Brosseau
GWGeorge A. Wells
George A. Wells
SPStéphane Poitras
Stéphane Poitras
PTPeter Tugwell
Peter Tugwell
LCLynn Casimiro
Lynn Casimiro
CCCourtney Cohoon
Courtney Cohoon

13 October 2012 in BMC Public Health
Verified
Journal Article
Open access
PDF file
LBLucie Brosseau
Lucie Brosseau
GWGeorge Wells
George Wells
ETEmily J Tetzlaff
Emily J Tetzlaff
RRRobert Reid
Robert Reid
AMAndreas Maetzel
Andreas Maetzel
LCLily Chen
Lily Chen
The implementation of evidence based clinical practice guidelines on self-management interventions to patients with chronic diseases is a complex process. A multifaceted strategy may offer an effective knowledge translation (KT) intervention to promote knowledge uptake and improve adherence in an effective walking program based on the Ottawa Panel Evidence Based Clinical Practice Guidelines among individuals with moderate osteoarthritis (OA). A single-blind, randomized control trial was conducted. Patients with mild to moderate (OA) of the knee (n=222) were randomized to one of three KT groups: 1) Walking and Behavioural intervention (WB) (18 males, 57 females) which included the supervised community-based aerobic walking program combined with a behavioural intervention and an educational pamphlet on the benefits of walking for OA; 2) Walking intervention (W) (24 males, 57 females) wherein participants only received the supervised community-based aerobic walking program intervention and the educational pamphlet; 3) Self-directed control (C) (32 males, 52 females) wherein participants only received the educational pamphlet. One-way analyses of variance were used to test for differences in quality of life, adherence, confidence, and clinical outcomes among the study groups at each 3 month assessment during the 12-month intervention period and 6-month follow-up period. Short-term program adherence was greater in WB compared to C (p 0.05) was observed for long-term adherence (6 to 12 months), and total adherence between the three groups. The three knowledge translation strategies demonstrated equivalent long-term results for the implementation of a walking program for older individuals with moderate OA. Lower dropout rates as well as higher retention rates were observed for WB at 12 and 18 months. The additional knowledge translation behavioural component facilitated the implementation of clinical practice guidelines on walking over a short-term period. More studies are needed to improve the long-term walking adherence or longer guidelines uptake on walking among participants with OA. Particular attention should be taken into account related to patient’s characteristic and preference. OA can be managed through the implementation of a walking program based on clinical practice guidelines in existing community-based walking clubs as well as at home with the minimal support of an exercise therapist or a trained volunteer. Current Controlled Trials IRSCTNO9193542