Dr. Jose R. Eguibar

Yawning is a common behavioral event that is observed in humans, as well as other mammals, birds and reptiles. In humans, yawning often occurs just before bed and upon waking up, and is also associated with tedious or boring situations. Although the physiologic roles of yawning have yet to be fully elucidated, the past 50 years of research has led to a much greater understanding of the neuropharmacologic regulation of yawning. While many of the early studies concluded that yawning was primarily driven by changes in cholinergic neurotransmission, we now know that numerous neurotransmitters and neurohormones are involved in the mediation of yawning, including acetylcholine, dopamine, glutamate, serotonin, oxytocin, GABA, opioids, adrenergics, nitric oxide, as well as the proopiomelanocortin-derived peptides ACTH and alpha-MSH. Furthermore, antagonist interaction studies have clearly defined at least 3 distinct neural pathways involved in the induction of yawning, as well as the hierarchical order through which these different neurotransmitter systems interact to regulate yawning. The following sections will discuss the state of knowledge for each of the major neurotransmitters and neurohormones involved in the regulation of yawning, their interactions with one another, and their place in the hierarchical organization of yawning.

1 February 2013 in Physiology & Behavior

Journal Article

Sperm count and sperm motility decrease in old rats

Rosa Angélica Lucio

José L. Tlachi-López

Jose R. Eguibar

AÅ

Anders Ågmo

About Me

Dr. Jose R. Eguibar studied Medical Doctor at Medical School of the Universidad Autónoma de Puebla with honors, then a master’s degree in Physiological Sciences at the Institute of Physiology and his PhD in Neuroscience at CINVESTAV graduated with honors. He is a full-time professor at the Institute of Physiology, Benemérita Universidad Autonoma de PueblaDr Eguibar. He has published more than 100 papers in indexed Journals, 41 book chapters in Spanish and seven in English, five books and 25 papers science divulgation; with more than 500 abstracts in International and Mexican scientific meetings. His papers received more than 1,890 cites, with Hirsh factor 26. He mentored 41 Bachelor Majors, 39 Master’s, and 15 PhD ́s and 3 postdoctoral fellows. Dr. Eguibar is member of the National Research System, the highest and he is distinguished professor from the Ministry of Education, and leader of the research group in Neuroendocrinology.Dr. Eguibar is regular member of 25 Research Societies such as Academia Mexicana de Ciencias and Academia Nacional de Medicina de México and he received different awards such as Premio “José Joaquín Izquierdo”, Premio Estatal en Tecnologías y Ciencias Médicas, 2004; as the best researcher in the state of Puebla. He also received aérito Civil award in “Ciencia y Tecnología” 2009, and the prestigious award “Gregorio Pérez Palacios” for his academic career as a scientist from Academia de Investigación en Biología de la Reporducción A.C.

Dr. Jose R. Eguibar

Dr. Jose R. Eguibar

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About Me