Vsevolod V. (Seva) Gurevich has completed his PhD at the age of 32 years from Shemyakin Institute of Bioorganic Chemistry, Moscow, Russia, and postdoctoral studies from Thomas Jefferson University, Philadelphia, PA. He is currently Professor of Pharmacology at Vanderbilt University and holds an Endowed Chair. He has published more than 200 papers in reputed journals and has been serving as an editorial board member of several journals. The main focus of the work in his lab is structure-function studies of arrestin proteins, that bind almost all of >800 G protein-coupled receptors in humans and dozens of non-receptor signaling proteins. The lab is using biochemistry, biophysics, and cell biology to elucidate arrestin elements involved in these interactions and to construct signaling-biased arrestins specifically targeting individual receptors and signaling pathways.
Research Keywords & Expertise
Cell Signaling
Protein Engineering
Structural Analysis
GPCR
arrestin
Fingerprints
85%
arrestin
39%
GPCR
5%
Cell Signaling
5%
Protein Engineering
5%
Structural Analysis
Short Biography
Vsevolod V. (Seva) Gurevich has completed his PhD at the age of 32 years from Shemyakin Institute of Bioorganic Chemistry, Moscow, Russia, and postdoctoral studies from Thomas Jefferson University, Philadelphia, PA. He is currently Professor of Pharmacology at Vanderbilt University and holds an Endowed Chair. He has published more than 200 papers in reputed journals and has been serving as an editorial board member of several journals. The main focus of the work in his lab is structure-function studies of arrestin proteins, that bind almost all of >800 G protein-coupled receptors in humans and dozens of non-receptor signaling proteins. The lab is using biochemistry, biophysics, and cell biology to elucidate arrestin elements involved in these interactions and to construct signaling-biased arrestins specifically targeting individual receptors and signaling pathways.
Well done!
