Valentín Hornillos

Dr. Valentín Hornillos

orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 January 2021 in Chemical Society Reviews
Verified
Journal Article
Open access
PDF file
JCJosé A. Carmona
José A. Carmona
CRCarlos Rodríguez-Franco
Carlos Rodríguez-Franco
RFRosario Fernández
Rosario Fernández
Valentín HornillosValentín Hornillos
Valentín Hornillos
JLJosé M. Lassaletta
José M. Lassaletta
Atroposelective transformations of (hetero)biaryls are classified into desymmetrization, kinetic resolution, dynamic kinetic resolution, and dynamic kinetic asymmetric transformation depending on the nature and behavior of the starting material.

25 March 2022 in Chemistry – A European Journal
Verified
Journal Article
Open access
PRPatricia Rodríguez‐Salamanca
Patricia Rodríguez‐Salamanca
RFRosario Fernández
Rosario Fernández
Valentín HornillosValentín Hornillos
Valentín Hornillos
JLJosé M. Lassaletta
José M. Lassaletta
Molecules with restricted rotation around a single bond or atropisomers are found in a wide number of natural products and bioactive molecules as well as in chiral ligands for asymmetric catalysis and smart materials. Although most of these compounds are biaryls and heterobiaryls displaying a C−C stereogenic axis, there is a growing interest in less common and more challenging axially chiral C−N atropisomers. This review offers an overview of the various methodologies available for their asymmetric synthesis. A brief introduction is initially given to contextualize these axially chiral skeletons, including a historical background and examples of natural products containing axially chiral C−N axes. The preparation of different families of C−N based atropisomers is then presented from anilides to chiral five‐ and six‐membered ring heterocycles. Special emphasis has been given to modern catalytic asymmetric strategies over the past decade for the synthesis of these chiral scaffolds. Applications of these methods to the preparation of natural products and biologically active molecules will be highlighted along the text.

10 January 2020 in Journal of the American Chemical Society
Verified
Journal Article
Closed access
ARAntonio Romero-Arenas
Antonio Romero-Arenas
Valentín HornillosValentín Hornillos
Valentín Hornillos
JIJavier Iglesias-Sigüenza
Javier Iglesias-Sigüenza
RFRosario Fernández
Rosario Fernández
JLJoaquin Lopez-Serrano
Joaquin Lopez-Serrano
JLJosé M. Lassaletta
José M. Lassaletta

13 August 2018 in Journal of the American Chemical Society
Verified
Journal Article
Closed access
JCJosé Alberto Carmona
José Alberto Carmona
Valentín HornillosValentín Hornillos
Valentín Hornillos
PRPedro Ramírez-López
Pedro Ramírez-López
ARAbel Ros
Abel Ros
JIJavier Iglesias-Sigüenza
Javier Iglesias-Sigüenza
JLJosé M. Lassaletta
José M. Lassaletta

6 March 2018 in Angewandte Chemie International Edition
Verified
Journal Article
Closed access
PDF file
Valentín HornillosValentín Hornillos
Valentín Hornillos
JCJose Alberto Carmona
Jose Alberto Carmona
ARAbel Ros
Abel Ros
JIJavier Iglesias-Sigüenza
Javier Iglesias-Sigüenza
JLJoaquin Lopez-Serrano
Joaquin Lopez-Serrano
JLJosé M. Lassaletta
José M. Lassaletta

27 January 2013 in Journal of the American Chemical Society
Verified
Journal Article
Closed access
Valentín HornillosValentín Hornillos
Valentín Hornillos
MPManuel Pérez
Manuel Pérez
MFMartín Fañanás-Mastral
Martín Fañanás-Mastral
BFBen L. Feringa
Ben L. Feringa