Recent advances in communication technologies and the Internet-of-Medical-Things (IOMT) have transformed smart healthcare enabled by artificial intelligence (AI). Traditionally, AI techniques require centralized data collection and processing that may be infeasible in realistic healthcare scenarios due to the high scalability of modern healthcare networks and growing data privacy concerns. Federated Learning (FL), as an emerging distributed collaborative AI paradigm, is particularly attractive for smart healthcare, by coordinating multiple clients (e.g., hospitals) to perform AI training without sharing raw data. Accordingly, we provide a comprehensive survey on the use of FL in smart healthcare. First, we present the recent advances in FL, the motivations, and the requirements of using FL in smart healthcare. The recent FL designs for smart healthcare are then discussed, ranging from resource-aware FL, secure and privacy-aware FL to incentive FL and personalized FL. Subsequently, we provide a state-of-the-art review on the emerging applications of FL in key healthcare domains, including health data management, remote health monitoring, medical imaging, and COVID-19 detection. Several recent FL-based smart healthcare projects are analyzed, and the key lessons learned from the survey are also highlighted. Finally, we discuss interesting research challenges and possible directions for future FL research in smart healthcare.

Emerging applications such as Internet of Everything, Holographic Telepresence, collaborative robots, and space and deep-sea tourism are already highlighting the limitations of existing fifth-generation (5G) mobile networks. These limitations are in terms of data-rate, latency, reliability, availability, processing, connection density and global coverage, spanning over ground, underwater and space. The sixth-generation (6G) of mobile networks are expected to burgeon in the coming decade to address these limitations. The development of 6G vision, applications, technologies and standards has already become a popular research theme in academia and the industry. In this paper, we provide a comprehensive survey of the current developments towards 6G. We highlight the societal and technological trends that initiate the drive towards 6G. Emerging applications to realize the demands raised by 6G driving trends are discussed subsequently. We also elaborate the requirements that are necessary to realize the 6G applications. Then we present the key enabling technologies in detail. We also outline current research projects and activities including standardization efforts towards the development of 6G. Finally, we summarize lessons learned from state-of-the-art research and discuss technical challenges that would shed a new light on future research directions towards 6G.

Driven by the emergence of new compute-intensive applications and the vision of the Internet of Things (IoT), it is foreseen that the emerging 5G network will face an unprecedented increase in traffic volume and computation demands. However, end users mostly have limited storage capacities and finite processing capabilities, thus how to run compute-intensive applications on resource-constrained users has recently become a natural concern. Mobile edge computing (MEC), a key technology in the emerging fifth generation (5G) network, can optimize mobile resources by hosting compute-intensive applications, process large data before sending to the cloud, provide the cloud-computing capabilities within the radio access network (RAN) in close proximity to mobile users, and offer context-aware services with the help of RAN information. Therefore, MEC enables a wide variety of applications, where the real-time response is strictly required, e.g., driverless vehicles, augmented reality, robotics, and immerse media. Indeed, the paradigm shift from 4G to 5G could become a reality with the advent of new technological concepts. The successful realization of MEC in the 5G network is still in its infancy and demands for constant efforts from both academic and industry communities. In this survey, we first provide a holistic overview of MEC technology and its potential use cases and applications. Then, we outline up-to-date researches on the integration of MEC with the new technologies that will be deployed in 5G and beyond. We also summarize testbeds and experimental evaluations, and open source activities, for edge computing. We further summarize lessons learned from state-of-the-art research works as well as discuss challenges and potential future directions for MEC research.

Mobile-edge computing (MEC) has been envisioned as a promising paradigm to handle the massive volume of data generated from ubiquitous mobile devices for enabling intelligent services with the help of artificial intelligence (AI). Traditionally, AI techniques often require centralized data collection and training in a single entity, e.g., an MEC server, which is now becoming a weak point due to data privacy concerns and high overhead of raw data communications. In this context, federated learning (FL) has been proposed to provide collaborative data training solutions, by coordinating multiple mobile devices to train a shared AI model without directly exposing their underlying data, which enjoys considerable privacy enhancement. To improve the security and scalability of FL implementation, blockchain as a ledger technology is attractive for realizing decentralized FL training without the need for any central server. Particularly, the integration of FL and blockchain leads to a new paradigm, called FLchain, which potentially transforms intelligent MEC networks into decentralized, secure, and privacy-enhancing systems. This article presents an overview of the fundamental concepts and explores the opportunities of FLchain in MEC networks. We identify several main issues in FLchain design, including communication cost, resource allocation, incentive mechanism, security and privacy protection. The key solutions and the lessons learned along with the outlooks are also discussed. Then, we investigate the applications of FLchain in popular MEC domains, such as edge data sharing, edge content caching and edge crowdsensing. Finally, important research challenges and future directions are also highlighted.