Our primary focus is to elucidate how malaria parasites signal in the various stages of their life cycle to explore new avenues for clinical intervention. My work in this area spans a broad range of malaria parasitology topics, including molecular biology and whole-genome scans, cellular imaging, and generation of parasite knock-out strains in the field of intracellular signaling in malaria parasites. Our lab was one of the first to investigate IP3-PLC and calcium signaling at proliferation and synchronization of intraerythrocytic stages of Plasmodium spp. Our laboratory engages in the screening of synthetic and natural compounds aiming to discover new antimalarial drugs. For more information, see http://www.usp.br/garciamalarialab/.
Research Keywords & Expertise
Calcium
Drug Discovery
Melatonin
Plasmodium falciparum
Cell Signalling
Calcium Homeostasis
Malaria,
calcium, cell signali...
Fingerprints
67%
Malaria,
58%
Plasmodium falciparum
31%
Calcium
26%
Melatonin
5%
Calcium Homeostasis
5%
Cell Signalling
Short Biography
Our primary focus is to elucidate how malaria parasites signal in the various stages of their life cycle to explore new avenues for clinical intervention. My work in this area spans a broad range of malaria parasitology topics, including molecular biology and whole-genome scans, cellular imaging, and generation of parasite knock-out strains in the field of intracellular signaling in malaria parasites. Our lab was one of the first to investigate IP3-PLC and calcium signaling at proliferation and synchronization of intraerythrocytic stages of Plasmodium spp. Our laboratory engages in the screening of synthetic and natural compounds aiming to discover new antimalarial drugs. For more information, see http://www.usp.br/garciamalarialab/.