Jaison Phour is a Registered Biomedical Scientist with interest and expertise in tumor pathology of glioblastoma. A major aspect of the current experimental work focuses on the resistance mechanism of temozolomide (TMZ) treatments in glioblastomas using CRISPR/dCas9 interference and activation as well as CRISPR KO to identify gene candidates involved in TMZ resistance mechanism. The on-going work focuses on functional analysis of the exact pathway and resistance mechanism of those genes in 2D and 3D tumor spheroids, organotypic tissue slice and in-vivo experiments.