Jean-Christophe P. Gabriel

Dr. Jean-Christophe P. Gabriel

NIMBE, CEA Saclay, Gif-sur-Yvette, Île-de-France, France
orcid

Research Focus & Metrics

Academic Career Length

34Years (1993-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 March 2003 in Nano Letters
Verified
Journal Article
Closed access
Alexander StarAlexander Star
Alexander Star
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel
KBKeith Bradley
Keith Bradley
GGGeorge Grüner
George Grüner

17 January 2006 in Proceedings of the National Academy of Sciences
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Journal Article
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Alexander StarAlexander Star
Alexander Star
ETEugene Tu
Eugene Tu
JNJoseph Niemann
Joseph Niemann
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel
CJC. Steve Joiner
C. Steve Joiner
CVChristian Valcke
Christian Valcke
We report carbon nanotube network field-effect transistors (NTNFETs) that function as selective detectors of DNA immobilization and hybridization. NTNFETs with immobilized synthetic oligonucleotides have been shown to specifically recognize target DNA sequences, including H63D single-nucleotide polymorphism (SNP) discrimination in the HFE gene, responsible for hereditary hemochromatosis. The electronic responses of NTNFETs upon single-stranded DNA immobilization and subsequent DNA hybridization events were confirmed by using fluorescence-labeled oligonucleotides and then were further explored for label-free DNA detection at picomolar to micromolar concentrations. We have also observed a strong effect of DNA counterions on the electronic response, thus suggesting a charge-based mechanism of DNA detection using NTNFET devices. Implementation of label-free electronic detection assays using NTNFETs constitutes an important step toward low-cost, low-complexity, highly sensitive and accurate molecular diagnostics.

1 October 2006 in The Journal of Physical Chemistry B
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Journal Article
Closed access
Alexander StarAlexander Star
Alexander Star
VJVikram Joshi
Vikram Joshi
SSSergei Skarupo
Sergei Skarupo
DTDavid Thomas
David Thomas
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel

29 October 2004 in Advanced Materials
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Journal Article
Closed access
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Alexander StarAlexander Star
Alexander Star
THT.‐R. Han
T.‐R. Han
VJV. Joshi
V. Joshi
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel
GGG. Grüner
G. Grüner

9 September 2003 in Nano Letters
Verified
Journal Article
Closed access
KBKeith Bradley
Keith Bradley
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel
GGGeorge Grüner
George Grüner

1 July 2001 in Chemical Reviews
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Journal Article
Closed access
Jean-Christophe P. GabrielJean-Christophe P. Gabriel
Jean-Christophe P. Gabriel
KBKamal Boubekeur
Kamal Boubekeur
SUSantiago Uriel
Santiago Uriel
PBPatrick Batail
Patrick Batail